Urban Air Pollution Particulates Suppress Human T-Cell Responses to Mycobacterium Tuberculosis

Tuberculosis (TB) and air pollution both contribute significantly to the global burden of disease. Epidemiological studies show that exposure to household and urban air pollution increase the risk of new infections with (M.tb) and the development of TB in persons infected with and alter treatment ou...

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Veröffentlicht in:	International journal of environmental research and public health 2019-10, Vol.16 (21), p.4112
Hauptverfasser:	Ibironke, Olufunmilola, Carranza, Claudia, Sarkar, Srijata, Torres, Martha, Choi, Hyejeong Theresa, Nwoko, Joyce, Black, Kathleen, Quintana-Belmares, Raul, Osornio-Vargas, Álvaro, Ohman-Strickland, Pamela, Schwander, Stephan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Air pollution Air Pollution - analysis Air pollution effects Autoclaving Blood Cell activation Cell culture Cities Climate change Cytokines Cytokines - metabolism Diagnostic Tests, Routine Diesel engines Experiments Exposure Female Flow cytometry Gene expression Glutamine Human behavior Humans Infections Inflammation Interferon regulatory factor 1 Leukocytes (mononuclear) Leukocytes, Mononuclear - metabolism Lymphocytes Lymphocytes T Macrophages Male Middle Aged Monocytes Mycobacterium tuberculosis - immunology Particulate emissions Particulate matter Particulate Matter - analysis Particulate Matter - metabolism Particulates Peripheral blood mononuclear cells Pollution Pollution effects Roofs Sonication Studies T-Lymphocytes - drug effects T-Lymphocytes - immunology TNF inhibitors Tuberculosis Tumor necrosis factor-TNF Tumor necrosis factor-α Young Adult γ-Interferon
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