Targetting an LncRNA P5848-ENO1 axis inhibits tumor growth in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) has a high recurrence rate and poor clinical outcome after currently used therapies, including radiofrequency ablation. To explore the possible mechanisms for the relapse of HCC, in the present study we focussed on long non-coding RNA (LncRNA), which has been reported...

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Veröffentlicht in:	Bioscience reports 2019-11, Vol.39 (11)
Hauptverfasser:	Zhu, Xidan, Yu, Hui, Li, Baolin, Quan, Jing, Zeng, Zhangrui, Li, Guangrong, Liu, Jinbo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - genetics Biomarkers, Tumor - genetics Cancer Carcinoma, Hepatocellular - genetics Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Cell Survival - genetics DNA-Binding Proteins - genetics Gene Expression & Regulation Gene Expression Regulation, Neoplastic - genetics Hep G2 Cells Humans Liver Neoplasms - genetics Male Mice Mice, Inbred BALB C Mice, Nude Neoplasm Invasiveness - genetics Phosphopyruvate Hydratase - genetics RNA, Long Noncoding - genetics RNA, Small Interfering - genetics Tumor Suppressor Proteins - genetics Up-Regulation - genetics
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