Sugarcoating Lung Injury: A Novel Role for High-Molecular-Weight Hyaluronan in Pneumonia
Garantziotis and Matalon reflect on the novel role of high-molecular-weight hyaluronan in pneumonia. Acute respiratory distress syndrome /acute lung injury (ALI) remains a severe sepsis and severe complication of pneumonia. Despite decades of clinical treatment trials, and active research, pharmacol...
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| Veröffentlicht in: | American journal of respiratory and critical care medicine 2019-11, Vol.200 (10), p.1197-1198 |
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| container_issue | 10 |
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| container_title | American journal of respiratory and critical care medicine |
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| creator | Garantziotis, Stavros Matalon, Sadis |
| description | Garantziotis and Matalon reflect on the novel role of high-molecular-weight hyaluronan in pneumonia. Acute respiratory distress syndrome /acute lung injury (ALI) remains a severe sepsis and severe complication of pneumonia. Despite decades of clinical treatment trials, and active research, pharmacological treatment is still lacking. The traditional pneumonic treatment has been to focus on the microbial component and use antibiotics for treatment. Also cited is the study by Liu and colleagues that examines the significance of extracellular vesicles (EVs) on the initiation and propagation of ALI. |
| doi_str_mv | 10.1164/rccm.201908-1554ED |
| format | Article |
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| identifier | ISSN: 1073-449X |
| ispartof | American journal of respiratory and critical care medicine, 2019-11, Vol.200 (10), p.1197-1198 |
| issn | 1073-449X 1535-4970 |
| language | eng |
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| source | MEDLINE; American Thoracic Society (ATS) Journals Online; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Antibiotics Humans Hyaluronic Acid Lung Lung Injury Molecular weight Pneumonia Pneumonia, Bacterial Respiratory distress syndrome |
| title | Sugarcoating Lung Injury: A Novel Role for High-Molecular-Weight Hyaluronan in Pneumonia |
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