Steady-state and regenerative hematopoiesis occurs normally in mice in the absence of GDF11

Tightly regulated production of mature blood cells is essential for health and survival in vertebrates and dependent on discrete populations of blood-forming (hematopoietic) stem and progenitor cells. Prior studies suggested that inhibition of growth differentiation factor 11 (GDF11) through soluble...

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Veröffentlicht in:	Blood 2019-11, Vol.134 (20), p.1712-1716
Hauptverfasser:	Goldstein, Jill M., Sengul, Hilal, Messemer, Kathleen A., Fernández-Alfara, Marcos, Garbern, Jessica C., Kristl, Amy C., Lee, Richard T., Wagers, Amy J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Morphogenetic Proteins - genetics Brief Report Cells, Cultured Female Gene Deletion Growth Differentiation Factors - genetics Hematopoiesis Hematopoiesis and Stem Cells Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - metabolism Male Mice
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