Role of edible mushroom as a potent therapeutics for the diabetes and obesity
Diabetes and obesity are the most frequently found disease worldwide. Several factors are responsible for obesity, i.e., imbalance in energy expenditure, environmental factors, feeding habit, lifestyle, etc., which can also be responsible for type 2 diabetes mellitus. There are several synthetic dru...
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| Veröffentlicht in: | 3 Biotech 2019-12, Vol.9 (12), p.450-450, Article 450 |
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| creator | Dubey, Sushil K. Chaturvedi, Vivek K. Mishra, Divya Bajpeyee, Anand Tiwari, Aprajita Singh, M. P. |
| description | Diabetes and obesity are the most frequently found disease worldwide. Several factors are responsible for obesity, i.e., imbalance in energy expenditure, environmental factors, feeding habit, lifestyle, etc., which can also be responsible for type 2 diabetes mellitus. There are several synthetic drugs available to combat these diseases which have some side effects on sufferers. Therefore, people are shifting towards inexpensive, effective, widely available natural and herbal medicines. Edible mushrooms, which have been used from ancient time to cure these diseases, contain anti-oxidant, fibers, triterpenoids, alkaloid, and other phytochemicals. Comatin, β-glucan, Tremellastin, and Lentinan KS-2 are active chemicals of mushrooms which show great effect on diabetes mellitus and obesity by modulating either cellular function or biochemical pathways. Here, in this review, we have discussed the potential role of edible mushrooms and its biochemicals in control of diabetes and obesity. Using Bioinformatics, we can find the specific targets of theses biochemicals, so that these can be more effective. |
| doi_str_mv | 10.1007/s13205-019-1982-3 |
| format | Article |
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P.</creator><creatorcontrib>Dubey, Sushil K. ; Chaturvedi, Vivek K. ; Mishra, Divya ; Bajpeyee, Anand ; Tiwari, Aprajita ; Singh, M. P.</creatorcontrib><description>Diabetes and obesity are the most frequently found disease worldwide. Several factors are responsible for obesity, i.e., imbalance in energy expenditure, environmental factors, feeding habit, lifestyle, etc., which can also be responsible for type 2 diabetes mellitus. There are several synthetic drugs available to combat these diseases which have some side effects on sufferers. Therefore, people are shifting towards inexpensive, effective, widely available natural and herbal medicines. Edible mushrooms, which have been used from ancient time to cure these diseases, contain anti-oxidant, fibers, triterpenoids, alkaloid, and other phytochemicals. Comatin, β-glucan, Tremellastin, and Lentinan KS-2 are active chemicals of mushrooms which show great effect on diabetes mellitus and obesity by modulating either cellular function or biochemical pathways. Here, in this review, we have discussed the potential role of edible mushrooms and its biochemicals in control of diabetes and obesity. Using Bioinformatics, we can find the specific targets of theses biochemicals, so that these can be more effective.</description><identifier>ISSN: 2190-572X</identifier><identifier>EISSN: 2190-5738</identifier><identifier>DOI: 10.1007/s13205-019-1982-3</identifier><identifier>PMID: 31832297</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>adverse effects ; Agriculture ; alkaloids ; Antidiabetics ; Antioxidants ; beta-glucans ; biochemical pathways ; Biochemistry ; Bioinformatics ; Biomaterials ; Biotechnology ; Cancer Research ; Chemistry ; Chemistry and Materials Science ; Diabetes ; Diabetes mellitus ; Diabetes mellitus (non-insulin dependent) ; Energy expenditure ; Environmental factors ; Glucan ; Herbal medicine ; herbal medicines ; Lentinan ; Mushrooms ; noninsulin-dependent diabetes mellitus ; Obesity ; Organic chemistry ; phytochemicals ; Review ; Review Article ; Side effects ; Stem Cells ; therapeutics ; Triterpenoids ; β-Glucan</subject><ispartof>3 Biotech, 2019-12, Vol.9 (12), p.450-450, Article 450</ispartof><rights>King Abdulaziz City for Science and Technology 2019</rights><rights>King Abdulaziz City for Science and Technology 2019.</rights><rights>Copyright Springer Nature B.V. 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c503t-ddb5a75d75e6aa3627277de598da3ca537be2266feba759f85be52f00e1f53ab3</citedby><cites>FETCH-LOGICAL-c503t-ddb5a75d75e6aa3627277de598da3ca537be2266feba759f85be52f00e1f53ab3</cites><orcidid>0000-0002-6236-856X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856246/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856246/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,41464,42533,51294,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31832297$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dubey, Sushil K.</creatorcontrib><creatorcontrib>Chaturvedi, Vivek K.</creatorcontrib><creatorcontrib>Mishra, Divya</creatorcontrib><creatorcontrib>Bajpeyee, Anand</creatorcontrib><creatorcontrib>Tiwari, Aprajita</creatorcontrib><creatorcontrib>Singh, M. P.</creatorcontrib><title>Role of edible mushroom as a potent therapeutics for the diabetes and obesity</title><title>3 Biotech</title><addtitle>3 Biotech</addtitle><addtitle>3 Biotech</addtitle><description>Diabetes and obesity are the most frequently found disease worldwide. Several factors are responsible for obesity, i.e., imbalance in energy expenditure, environmental factors, feeding habit, lifestyle, etc., which can also be responsible for type 2 diabetes mellitus. There are several synthetic drugs available to combat these diseases which have some side effects on sufferers. Therefore, people are shifting towards inexpensive, effective, widely available natural and herbal medicines. Edible mushrooms, which have been used from ancient time to cure these diseases, contain anti-oxidant, fibers, triterpenoids, alkaloid, and other phytochemicals. Comatin, β-glucan, Tremellastin, and Lentinan KS-2 are active chemicals of mushrooms which show great effect on diabetes mellitus and obesity by modulating either cellular function or biochemical pathways. Here, in this review, we have discussed the potential role of edible mushrooms and its biochemicals in control of diabetes and obesity. Using Bioinformatics, we can find the specific targets of theses biochemicals, so that these can be more effective.</description><subject>adverse effects</subject><subject>Agriculture</subject><subject>alkaloids</subject><subject>Antidiabetics</subject><subject>Antioxidants</subject><subject>beta-glucans</subject><subject>biochemical pathways</subject><subject>Biochemistry</subject><subject>Bioinformatics</subject><subject>Biomaterials</subject><subject>Biotechnology</subject><subject>Cancer Research</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Energy expenditure</subject><subject>Environmental factors</subject><subject>Glucan</subject><subject>Herbal medicine</subject><subject>herbal medicines</subject><subject>Lentinan</subject><subject>Mushrooms</subject><subject>noninsulin-dependent diabetes mellitus</subject><subject>Obesity</subject><subject>Organic chemistry</subject><subject>phytochemicals</subject><subject>Review</subject><subject>Review Article</subject><subject>Side effects</subject><subject>Stem Cells</subject><subject>therapeutics</subject><subject>Triterpenoids</subject><subject>β-Glucan</subject><issn>2190-572X</issn><issn>2190-5738</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNqNkU1LxDAQhoMoKro_wIsEvHip5qNpmosg4hcogih4C0kzdSttsyat4L83y67rBwjmMkPmyTuTeRHao-SIEiKPI-WMiIxQlVFVsoyvoW1GFcmE5OX6KmdPW2gS4wtJR1ChKNlEW5yWnDElt9HtvW8B-xqDa2zKujFOg_cdNhEbPPMD9AMephDMDMahqSKufZhfYNcYCwMkrHfYW4jN8L6LNmrTRpgs4w56vDh_OLvKbu4ur89Ob7JKED5kzllhpHBSQGEML5hkUjoQqnSGV0ZwaYGxoqjBJkzVpbAgWE0I0FpwY_kOOlnozkbbgavSkMG0ehaazoR37U2jf1b6Zqqf_ZsuSlGwvEgCh0uB4F9HiIPumlhB25oe_Bg144Llec5J_g-UlTxXquQJPfiFvvgx9GkTiaK5UDJXNFF0QVXBxxigXs1NiZ5bqxfW6mStnlur58r73z-8evFpZALYAoip1D9D-Gr9t-oHYDiuyw</recordid><startdate>20191201</startdate><enddate>20191201</enddate><creator>Dubey, Sushil K.</creator><creator>Chaturvedi, Vivek K.</creator><creator>Mishra, Divya</creator><creator>Bajpeyee, Anand</creator><creator>Tiwari, Aprajita</creator><creator>Singh, M. 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| subjects | adverse effects Agriculture alkaloids Antidiabetics Antioxidants beta-glucans biochemical pathways Biochemistry Bioinformatics Biomaterials Biotechnology Cancer Research Chemistry Chemistry and Materials Science Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Energy expenditure Environmental factors Glucan Herbal medicine herbal medicines Lentinan Mushrooms noninsulin-dependent diabetes mellitus Obesity Organic chemistry phytochemicals Review Review Article Side effects Stem Cells therapeutics Triterpenoids β-Glucan |
| title | Role of edible mushroom as a potent therapeutics for the diabetes and obesity |
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