Recombinant human monoclonal HLA antibodies of different IgG subclasses recognising the same epitope: Excellent tools to study differential effects of donor‐specific antibodies

In the field of transplantation, the humoural immune response against mismatched HLA antigens of the donor is associated with inferior graft survival, but not in every patient. Donor‐specific HLA antibodies (DSA) of different immunoglobulin G (IgG) subclasses may have differential effects on the tra...

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Veröffentlicht in:HLA 2019-11, Vol.94 (5), p.415-424
Hauptverfasser: Kramer, Cynthia S. M., Franke‐van Dijk, Marry E. I., Priddey, Ashley J., Pongrácz, Tamás, Gnudi, Elena, Car, Helena, Karahan, Gonca E., Beelen, Els, Zilvold‐van den Oever, Chalana C. C., Rademaker, Hendrik J., Haan, Noortje, Wuhrer, Manfred, Kosmoliaptsis, Vasilis, Parren, Paul W. H. I., Mulder, Arend, Roelen, Dave L., Claas, Frans H. J., Heidt, Sebastiaan
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Sprache:eng
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