Signs of enhanced formation of gist memory in children with autism spectrum disorder – a study of memory functions of sleep
Background Autism spectrum disorder (ASD) is characterized by impaired cognitive and social skills, including emotional dysregulation, and symptoms have been suspected to partly arise from impaired formation of memory representations regulating these behaviours. Sleep, which is subjectively impaired...
Gespeichert in:
| Veröffentlicht in: | Journal of child psychology and psychiatry 2019-08, Vol.60 (8), p.907-916 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 916 |
|---|---|
| container_issue | 8 |
| container_start_page | 907 |
| container_title | Journal of child psychology and psychiatry |
| container_volume | 60 |
| creator | Kurz, Eva‐Maria Conzelmann, Annette Barth, Gottfried Maria Hepp, Lisa Schenk, Damaris Renner, Tobias J. Born, Jan Zinke, Katharina |
| description | Background
Autism spectrum disorder (ASD) is characterized by impaired cognitive and social skills, including emotional dysregulation, and symptoms have been suspected to partly arise from impaired formation of memory representations regulating these behaviours. Sleep, which is subjectively impaired in ASD, is critical for forming long‐term memories and ed gist‐based representations. We expected a generally reduced memory benefit from sleep in children with ASD, and a diminished enhancement of gist representations, in particular.
Methods
We compared effects of sleep on memory consolidation between boys (9–12 years) with ASD (n = 21) and typically developing (TD, n = 20) boys, matched for age and IQ, in a within‐subjects crossover design. We employed an emotional picture recognition task and the Deese–Roediger–McDermott (DRM) word list task for assessing gist memory formation in the emotional and nonemotional domain, respectively. Learning took place before retention intervals of nocturnal sleep and daytime wakefulness, and retrieval was tested afterwards.
Results
Surprisingly, on the DRM task, children with ASD showed an enhanced sleep‐dependent formation of gist‐based memory (i.e. more recall of ‘critical lure words’ after sleep compared to wakefulness) than TD children, with this effect occurring on top of a diminished veridical word memory. On the picture recognition task, children with ASD also showed a stronger emotional enhancement in memory (i.e. relatively better memory for negative than neutral pictures) than TD children, with this enhancement occurring independent of sleep. Sleep polysomnography was remarkably comparable between groups.
Conclusions
Children with ASD show well‐preserved sleep‐dependent memory consolidation. Enhanced gist memory formation in these children might reflect a compensatory response for impairments at earlier stages of memory processing, that is during encoding. |
| doi_str_mv | 10.1111/jcpp.13048 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6850042</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2258590084</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4488-1b37de15e3e8feb454b346939fbd10724232ec0af2e0fb038f64dbacabb2d4613</originalsourceid><addsrcrecordid>eNp9kc2KFDEQx4Mo7jh68QEk4EWEWSsf3ZO-CMvgJwsuqOeQTldmMnQnbdLtMgfBd_ANfRK7d8ZFPZhLIPXLr6r4E_KYwTmbzou97ftzJkCqO2TBZFmt1iWDu2QBwNmqKgWckQc57wGgFIW6T84EVKBKWS3It49-GzKNjmLYmWCxoS6mzgw-hvl16_NAO-xiOlAfqN35tkkY6LUfdtSMg88dzT3aIY0dbXyOqcFEf37_QQ3Nw9gcZsnpvxuDnb037XKL2D8k95xpMz463Uvy-fWrT5u3q8sPb95tLi5XVkqlVqwW6wZZgQKVw1oWshbTmqJydcNgzSUXHC0YxxFcDUK5Uja1saaueSNLJpbk5dHbj3WHjcUwJNPqPvnOpIOOxuu_K8Hv9DZ-1aUqACb9kjw7CVL8MmIedOezxbY1AeOYNWfVWqkSOEzo03_QfRxTmNbTnBeqqACUnKjnR8qmmHNCdzsMAz2nqudU9U2qE_zkz_Fv0d8xTgA7Ate-xcN_VPr95urqKP0FPGew1A</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2258590084</pqid></control><display><type>article</type><title>Signs of enhanced formation of gist memory in children with autism spectrum disorder – a study of memory functions of sleep</title><source>Applied Social Sciences Index & Abstracts (ASSIA)</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Kurz, Eva‐Maria ; Conzelmann, Annette ; Barth, Gottfried Maria ; Hepp, Lisa ; Schenk, Damaris ; Renner, Tobias J. ; Born, Jan ; Zinke, Katharina</creator><creatorcontrib>Kurz, Eva‐Maria ; Conzelmann, Annette ; Barth, Gottfried Maria ; Hepp, Lisa ; Schenk, Damaris ; Renner, Tobias J. ; Born, Jan ; Zinke, Katharina</creatorcontrib><description>Background
Autism spectrum disorder (ASD) is characterized by impaired cognitive and social skills, including emotional dysregulation, and symptoms have been suspected to partly arise from impaired formation of memory representations regulating these behaviours. Sleep, which is subjectively impaired in ASD, is critical for forming long‐term memories and ed gist‐based representations. We expected a generally reduced memory benefit from sleep in children with ASD, and a diminished enhancement of gist representations, in particular.
Methods
We compared effects of sleep on memory consolidation between boys (9–12 years) with ASD (n = 21) and typically developing (TD, n = 20) boys, matched for age and IQ, in a within‐subjects crossover design. We employed an emotional picture recognition task and the Deese–Roediger–McDermott (DRM) word list task for assessing gist memory formation in the emotional and nonemotional domain, respectively. Learning took place before retention intervals of nocturnal sleep and daytime wakefulness, and retrieval was tested afterwards.
Results
Surprisingly, on the DRM task, children with ASD showed an enhanced sleep‐dependent formation of gist‐based memory (i.e. more recall of ‘critical lure words’ after sleep compared to wakefulness) than TD children, with this effect occurring on top of a diminished veridical word memory. On the picture recognition task, children with ASD also showed a stronger emotional enhancement in memory (i.e. relatively better memory for negative than neutral pictures) than TD children, with this enhancement occurring independent of sleep. Sleep polysomnography was remarkably comparable between groups.
Conclusions
Children with ASD show well‐preserved sleep‐dependent memory consolidation. Enhanced gist memory formation in these children might reflect a compensatory response for impairments at earlier stages of memory processing, that is during encoding.</description><identifier>ISSN: 0021-9630</identifier><identifier>EISSN: 1469-7610</identifier><identifier>DOI: 10.1111/jcpp.13048</identifier><identifier>PMID: 30908649</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Acknowledgment ; Animal memory ; Autism ; Autism spectrum disorder ; Autism Spectrum Disorders ; Autistic children ; Boys ; Child & adolescent psychiatry ; Deese‐Roediger‐McDermott ; Emotion recognition ; emotional memory ; Emotional regulation ; Encoding ; gist abstraction ; Intelligence tests ; Interpersonal Competence ; Memories ; Memory ; memory consolidation ; Original ; Polysomnography ; Retrieval ; Sleep ; Sleep disorders ; Social skills ; Vocabulary ; Word Lists</subject><ispartof>Journal of child psychology and psychiatry, 2019-08, Vol.60 (8), p.907-916</ispartof><rights>2019 The Authors. Journal of Child Psychology and Psychiatry published by John Wiley & Sons Ltd on behalf of Association for Child and Adolescent Mental Health.</rights><rights>Copyright © 2019 Association for Child and Adolescent Mental Health</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4488-1b37de15e3e8feb454b346939fbd10724232ec0af2e0fb038f64dbacabb2d4613</citedby><cites>FETCH-LOGICAL-c4488-1b37de15e3e8feb454b346939fbd10724232ec0af2e0fb038f64dbacabb2d4613</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjcpp.13048$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjcpp.13048$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,1411,27901,27902,30976,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30908649$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kurz, Eva‐Maria</creatorcontrib><creatorcontrib>Conzelmann, Annette</creatorcontrib><creatorcontrib>Barth, Gottfried Maria</creatorcontrib><creatorcontrib>Hepp, Lisa</creatorcontrib><creatorcontrib>Schenk, Damaris</creatorcontrib><creatorcontrib>Renner, Tobias J.</creatorcontrib><creatorcontrib>Born, Jan</creatorcontrib><creatorcontrib>Zinke, Katharina</creatorcontrib><title>Signs of enhanced formation of gist memory in children with autism spectrum disorder – a study of memory functions of sleep</title><title>Journal of child psychology and psychiatry</title><addtitle>J Child Psychol Psychiatry</addtitle><description>Background
Autism spectrum disorder (ASD) is characterized by impaired cognitive and social skills, including emotional dysregulation, and symptoms have been suspected to partly arise from impaired formation of memory representations regulating these behaviours. Sleep, which is subjectively impaired in ASD, is critical for forming long‐term memories and ed gist‐based representations. We expected a generally reduced memory benefit from sleep in children with ASD, and a diminished enhancement of gist representations, in particular.
Methods
We compared effects of sleep on memory consolidation between boys (9–12 years) with ASD (n = 21) and typically developing (TD, n = 20) boys, matched for age and IQ, in a within‐subjects crossover design. We employed an emotional picture recognition task and the Deese–Roediger–McDermott (DRM) word list task for assessing gist memory formation in the emotional and nonemotional domain, respectively. Learning took place before retention intervals of nocturnal sleep and daytime wakefulness, and retrieval was tested afterwards.
Results
Surprisingly, on the DRM task, children with ASD showed an enhanced sleep‐dependent formation of gist‐based memory (i.e. more recall of ‘critical lure words’ after sleep compared to wakefulness) than TD children, with this effect occurring on top of a diminished veridical word memory. On the picture recognition task, children with ASD also showed a stronger emotional enhancement in memory (i.e. relatively better memory for negative than neutral pictures) than TD children, with this enhancement occurring independent of sleep. Sleep polysomnography was remarkably comparable between groups.
Conclusions
Children with ASD show well‐preserved sleep‐dependent memory consolidation. Enhanced gist memory formation in these children might reflect a compensatory response for impairments at earlier stages of memory processing, that is during encoding.</description><subject>Acknowledgment</subject><subject>Animal memory</subject><subject>Autism</subject><subject>Autism spectrum disorder</subject><subject>Autism Spectrum Disorders</subject><subject>Autistic children</subject><subject>Boys</subject><subject>Child & adolescent psychiatry</subject><subject>Deese‐Roediger‐McDermott</subject><subject>Emotion recognition</subject><subject>emotional memory</subject><subject>Emotional regulation</subject><subject>Encoding</subject><subject>gist abstraction</subject><subject>Intelligence tests</subject><subject>Interpersonal Competence</subject><subject>Memories</subject><subject>Memory</subject><subject>memory consolidation</subject><subject>Original</subject><subject>Polysomnography</subject><subject>Retrieval</subject><subject>Sleep</subject><subject>Sleep disorders</subject><subject>Social skills</subject><subject>Vocabulary</subject><subject>Word Lists</subject><issn>0021-9630</issn><issn>1469-7610</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>7QJ</sourceid><recordid>eNp9kc2KFDEQx4Mo7jh68QEk4EWEWSsf3ZO-CMvgJwsuqOeQTldmMnQnbdLtMgfBd_ANfRK7d8ZFPZhLIPXLr6r4E_KYwTmbzou97ftzJkCqO2TBZFmt1iWDu2QBwNmqKgWckQc57wGgFIW6T84EVKBKWS3It49-GzKNjmLYmWCxoS6mzgw-hvl16_NAO-xiOlAfqN35tkkY6LUfdtSMg88dzT3aIY0dbXyOqcFEf37_QQ3Nw9gcZsnpvxuDnb037XKL2D8k95xpMz463Uvy-fWrT5u3q8sPb95tLi5XVkqlVqwW6wZZgQKVw1oWshbTmqJydcNgzSUXHC0YxxFcDUK5Uja1saaueSNLJpbk5dHbj3WHjcUwJNPqPvnOpIOOxuu_K8Hv9DZ-1aUqACb9kjw7CVL8MmIedOezxbY1AeOYNWfVWqkSOEzo03_QfRxTmNbTnBeqqACUnKjnR8qmmHNCdzsMAz2nqudU9U2qE_zkz_Fv0d8xTgA7Ate-xcN_VPr95urqKP0FPGew1A</recordid><startdate>201908</startdate><enddate>201908</enddate><creator>Kurz, Eva‐Maria</creator><creator>Conzelmann, Annette</creator><creator>Barth, Gottfried Maria</creator><creator>Hepp, Lisa</creator><creator>Schenk, Damaris</creator><creator>Renner, Tobias J.</creator><creator>Born, Jan</creator><creator>Zinke, Katharina</creator><general>Blackwell Publishing Ltd</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201908</creationdate><title>Signs of enhanced formation of gist memory in children with autism spectrum disorder – a study of memory functions of sleep</title><author>Kurz, Eva‐Maria ; Conzelmann, Annette ; Barth, Gottfried Maria ; Hepp, Lisa ; Schenk, Damaris ; Renner, Tobias J. ; Born, Jan ; Zinke, Katharina</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4488-1b37de15e3e8feb454b346939fbd10724232ec0af2e0fb038f64dbacabb2d4613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Acknowledgment</topic><topic>Animal memory</topic><topic>Autism</topic><topic>Autism spectrum disorder</topic><topic>Autism Spectrum Disorders</topic><topic>Autistic children</topic><topic>Boys</topic><topic>Child & adolescent psychiatry</topic><topic>Deese‐Roediger‐McDermott</topic><topic>Emotion recognition</topic><topic>emotional memory</topic><topic>Emotional regulation</topic><topic>Encoding</topic><topic>gist abstraction</topic><topic>Intelligence tests</topic><topic>Interpersonal Competence</topic><topic>Memories</topic><topic>Memory</topic><topic>memory consolidation</topic><topic>Original</topic><topic>Polysomnography</topic><topic>Retrieval</topic><topic>Sleep</topic><topic>Sleep disorders</topic><topic>Social skills</topic><topic>Vocabulary</topic><topic>Word Lists</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kurz, Eva‐Maria</creatorcontrib><creatorcontrib>Conzelmann, Annette</creatorcontrib><creatorcontrib>Barth, Gottfried Maria</creatorcontrib><creatorcontrib>Hepp, Lisa</creatorcontrib><creatorcontrib>Schenk, Damaris</creatorcontrib><creatorcontrib>Renner, Tobias J.</creatorcontrib><creatorcontrib>Born, Jan</creatorcontrib><creatorcontrib>Zinke, Katharina</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of child psychology and psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kurz, Eva‐Maria</au><au>Conzelmann, Annette</au><au>Barth, Gottfried Maria</au><au>Hepp, Lisa</au><au>Schenk, Damaris</au><au>Renner, Tobias J.</au><au>Born, Jan</au><au>Zinke, Katharina</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Signs of enhanced formation of gist memory in children with autism spectrum disorder – a study of memory functions of sleep</atitle><jtitle>Journal of child psychology and psychiatry</jtitle><addtitle>J Child Psychol Psychiatry</addtitle><date>2019-08</date><risdate>2019</risdate><volume>60</volume><issue>8</issue><spage>907</spage><epage>916</epage><pages>907-916</pages><issn>0021-9630</issn><eissn>1469-7610</eissn><abstract>Background
Autism spectrum disorder (ASD) is characterized by impaired cognitive and social skills, including emotional dysregulation, and symptoms have been suspected to partly arise from impaired formation of memory representations regulating these behaviours. Sleep, which is subjectively impaired in ASD, is critical for forming long‐term memories and ed gist‐based representations. We expected a generally reduced memory benefit from sleep in children with ASD, and a diminished enhancement of gist representations, in particular.
Methods
We compared effects of sleep on memory consolidation between boys (9–12 years) with ASD (n = 21) and typically developing (TD, n = 20) boys, matched for age and IQ, in a within‐subjects crossover design. We employed an emotional picture recognition task and the Deese–Roediger–McDermott (DRM) word list task for assessing gist memory formation in the emotional and nonemotional domain, respectively. Learning took place before retention intervals of nocturnal sleep and daytime wakefulness, and retrieval was tested afterwards.
Results
Surprisingly, on the DRM task, children with ASD showed an enhanced sleep‐dependent formation of gist‐based memory (i.e. more recall of ‘critical lure words’ after sleep compared to wakefulness) than TD children, with this effect occurring on top of a diminished veridical word memory. On the picture recognition task, children with ASD also showed a stronger emotional enhancement in memory (i.e. relatively better memory for negative than neutral pictures) than TD children, with this enhancement occurring independent of sleep. Sleep polysomnography was remarkably comparable between groups.
Conclusions
Children with ASD show well‐preserved sleep‐dependent memory consolidation. Enhanced gist memory formation in these children might reflect a compensatory response for impairments at earlier stages of memory processing, that is during encoding.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>30908649</pmid><doi>10.1111/jcpp.13048</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-9630 |
| ispartof | Journal of child psychology and psychiatry, 2019-08, Vol.60 (8), p.907-916 |
| issn | 0021-9630 1469-7610 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6850042 |
| source | Applied Social Sciences Index & Abstracts (ASSIA); Wiley Online Library Journals Frontfile Complete |
| subjects | Acknowledgment Animal memory Autism Autism spectrum disorder Autism Spectrum Disorders Autistic children Boys Child & adolescent psychiatry Deese‐Roediger‐McDermott Emotion recognition emotional memory Emotional regulation Encoding gist abstraction Intelligence tests Interpersonal Competence Memories Memory memory consolidation Original Polysomnography Retrieval Sleep Sleep disorders Social skills Vocabulary Word Lists |
| title | Signs of enhanced formation of gist memory in children with autism spectrum disorder – a study of memory functions of sleep |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T12%3A16%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Signs%20of%20enhanced%20formation%20of%20gist%20memory%20in%20children%20with%20autism%20spectrum%20disorder%20%E2%80%93%20a%20study%20of%20memory%20functions%20of%20sleep&rft.jtitle=Journal%20of%20child%20psychology%20and%20psychiatry&rft.au=Kurz,%20Eva%E2%80%90Maria&rft.date=2019-08&rft.volume=60&rft.issue=8&rft.spage=907&rft.epage=916&rft.pages=907-916&rft.issn=0021-9630&rft.eissn=1469-7610&rft_id=info:doi/10.1111/jcpp.13048&rft_dat=%3Cproquest_pubme%3E2258590084%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2258590084&rft_id=info:pmid/30908649&rfr_iscdi=true |