Ossifying Fibroma of Maxilla in a Female Affected by Neurofibromatosis Type 1

Ossifying fibroma is a benign fibro-osseous lesion found exclusively in jaws. It has a predilection for premolar–molar region in the mandible. The occurrence of OF as solitary lesions with no underlying disease is common in jaws. However its co-existence in patients with neurofibromatosis type 1 (NF...

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Veröffentlicht in:Indian journal of otolaryngology, and head, and neck surgery and head, and neck surgery, 2019-11, Vol.71 (Suppl 3), p.2087-2090
Hauptverfasser: Jendi, Shoeb Kasim, Khatib, Shuaib, Mistry, Jagruti, Wagh, Ashwin, Vaidya, Kedar, Kokane, Gauri
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container_issue Suppl 3
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container_title Indian journal of otolaryngology, and head, and neck surgery
container_volume 71
creator Jendi, Shoeb Kasim
Khatib, Shuaib
Mistry, Jagruti
Wagh, Ashwin
Vaidya, Kedar
Kokane, Gauri
description Ossifying fibroma is a benign fibro-osseous lesion found exclusively in jaws. It has a predilection for premolar–molar region in the mandible. The occurrence of OF as solitary lesions with no underlying disease is common in jaws. However its co-existence in patients with neurofibromatosis type 1 (NF1) has not been described in jaws. NF1, also known as von Recklinghausen’s disease or peripheral neurofibromatosis, is an autosomal dominant multisystem disorder that approximately affects 1 in 2500–3000 births. The common manifestations of this disease include Café-au-lait macules, skinfold freckling, cutaneous neurofibromas, blue-red and pseudoatrophic macules on skin, plexiform neurofibroma, scoliosis, optic glioma. So far only one case of ossifying fibroma (OF) in such patients has been reported in the skull but not in the maxillofacial region. We report a case of OF of the maxilla in a 45 year old female suffering from NF1. To the best of our knowledge this is the first case report where OF occurred in the maxilla in patient with NF1.
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subjects Brain cancer
Clinical Report
Genetic disorders
Glioma
Head & neck cancer
Head and Neck Surgery
Jaw
Maxillofacial surgery
Medicine
Medicine & Public Health
Neurological disorders
Otolaryngology
Otorhinolaryngology
Tumors
title Ossifying Fibroma of Maxilla in a Female Affected by Neurofibromatosis Type 1
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