CBMT-08. IN VIVO EVALUATION OF PENTOSE PHOSPHATE PATHWAY ACTIVITY IN ORTHOTOPIC GLIOMA USING HYPERPOLARIZED δ-[1-13C]GLUCONOLACTONE

Abstract The pentose phosphate pathway (PPP) generates NADPH and ribose 5-phosphate, which are involved in the scavenging of reactive oxygen species and the synthesis of nucleotides. As such, the PPP is typically upregulated in cancer cells to address the metabolic needs of rapid cell proliferation....

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Veröffentlicht in:	Neuro-oncology (Charlottesville, Va.) Va.), 2019-11, Vol.21 (Supplement_6), p.vi34-vi34
Hauptverfasser:	Batsios, Georgios, Viswanath, Pavithra, Cao, Peng, Taglang, Celine, Subramani, Elavarasan, Flavell, Robert, Larson, Peder, Ronen, Sabrina
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Biology and Metabolism
Online-Zugang:	Volltext
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