Maf1 ameliorates cardiac hypertrophy by inhibiting RNA polymerase III through ERK1/2

: An imbalance between protein synthesis and degradation is one of the mechanisms of cardiac hypertrophy. Increased transcription in cardiomyocytes can lead to excessive protein synthesis and cardiac hypertrophy. Maf1 is an RNA polymerase III (RNA pol III) inhibitor that plays a pivotal role in regu...

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Veröffentlicht in:	Theranostics 2019-01, Vol.9 (24), p.7268-7281
Hauptverfasser:	Sun, Yu, Chen, Cong, Xue, Ruicong, Wang, Yan, Dong, Bin, Li, Jiayong, Chen, Chen, Jiang, Jingzhou, Fan, Wendong, Liang, Zhuomin, Huang, Huiling, Fang, Rong, Dai, Gang, Yan, Youchen, Yang, Tiqun, Li, Xiangxue, Huang, Zhan-Peng, Dong, Yugang, Liu, Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses Cardiomyocytes Fibroblasts Kinases Laboratory animals Protein synthesis Proteins Research Paper RNA polymerase Surgery Transcription factors
Online-Zugang:	Volltext
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