Natural Killer Cell Therapy: A New Treatment Paradigm for Solid Tumors

In treatments of solid tumors, adoptive transfer of ex vivo expanded natural killer (NK) cells has dawned as a new paradigm. Compared with cytotoxic T lymphocytes, NK cells take a unique position targeting tumor cells that evade the host immune surveillance by down-regulating self-antigen presentati...

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Veröffentlicht in:	Cancers 2019-10, Vol.11 (10), p.1534
Hauptverfasser:	Oh, Sooyeon, Lee, Joo-Ho, Kwack, KyuBum, Choi, Sang-Woon
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive transfer Adverse events Antigen presentation Antigens Antitumor activity Autoantigens Autografts Cancer Cell culture Cell therapy Clinical trials Cytokines Cytotoxicity Dendritic cells Ewings sarcoma Haplotypes Histocompatibility antigen HLA Immune checkpoint Immune system Immunosurveillance Immunotherapy Killer cell immunoglobulin-like receptors Leukemia Lymphocytes T Microenvironments Natural killer cells Review Solid tumors Stem cells Tumor cells Tumors Viral infections
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