Epitope peptides of Helicobacter pylori CagA antibodies from sera by whole-peptide mapping

Background Helicobacter pylori CagA has been found to be immuno-dominant protein and utilized for the diagnosis of the infection with cagA -positive strains. It is important to characterize the peptide epitopes capable of detecting serum anti-CagA antibodies to understand CagA immunogenicity. Method...

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Veröffentlicht in:	Journal of gastroenterology 2019-12, Vol.54 (12), p.1039-1051
Hauptverfasser:	Ansari, Shamshul, Akada, Junko, Matsuo, Yuichi, Shiota, Seiji, Kudo, Yoko, Okimoto, Tadayoshi, Murakami, Kazunari, Yamaoka, Yoshio
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Amino acids Antigenic determinants Colorectal Surgery Conserved sequence Enzyme-linked immunosorbent assay Epitope mapping Ethylenediaminetetraacetic acid Gastroenterology Genetic aspects Health aspects Helicobacter infections Helicobacter pylori Hepatology Immunogenicity Immunoglobulin G Infection Medical colleges Medicine Medicine & Public Health Original Article—Alimentary Tract Peptide mapping Peptides Phosphorylation Surgical Oncology Tyrosine
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