Virus evolution in Wolbachia- infected Drosophila
, a common vertically transmitted symbiont, can protect insects against viral infection and prevent mosquitoes from transmitting viral pathogens. For this reason, infected mosquitoes are being released to prevent the transmission of dengue and other arboviruses. An important question for the long-te...
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| Veröffentlicht in: | Proceedings of the Royal Society. B, Biological sciences Biological sciences, 2019-11, Vol.286 (1914), p.20192117 |
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| container_issue | 1914 |
| container_start_page | 20192117 |
| container_title | Proceedings of the Royal Society. B, Biological sciences |
| container_volume | 286 |
| creator | Martinez, Julien Bruner-Montero, Gaspar Arunkumar, Ramesh Smith, Sophia C L Day, Jonathan P Longdon, Ben Jiggins, Francis M |
| description | , a common vertically transmitted symbiont, can protect insects against viral infection and prevent mosquitoes from transmitting viral pathogens. For this reason,
infected mosquitoes are being released to prevent the transmission of dengue and other arboviruses. An important question for the long-term success of these programmes is whether viruses can evolve to escape the antiviral effects of
We have found that
altered the outcome of competition between strains of the DCV virus in
However,
still effectively blocked the virus genotypes that were favoured in the presence of the symbiont. We conclude that
did cause an evolutionary response in viruses, but this has little or no impact on the effectiveness of virus blocking. |
| doi_str_mv | 10.1098/rspb.2019.2117 |
| format | Article |
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infected mosquitoes are being released to prevent the transmission of dengue and other arboviruses. An important question for the long-term success of these programmes is whether viruses can evolve to escape the antiviral effects of
We have found that
altered the outcome of competition between strains of the DCV virus in
However,
still effectively blocked the virus genotypes that were favoured in the presence of the symbiont. We conclude that
did cause an evolutionary response in viruses, but this has little or no impact on the effectiveness of virus blocking.</description><identifier>ISSN: 0962-8452</identifier><identifier>ISSN: 1471-2954</identifier><identifier>EISSN: 1471-2954</identifier><identifier>DOI: 10.1098/rspb.2019.2117</identifier><identifier>PMID: 31662085</identifier><language>eng</language><publisher>England: The Royal Society</publisher><subject>Aedes ; Animals ; Culicidae ; Drosophila - microbiology ; Drosophila - physiology ; Evolution ; Symbiosis ; Virus Diseases ; Viruses ; Wolbachia - physiology</subject><ispartof>Proceedings of the Royal Society. B, Biological sciences, 2019-11, Vol.286 (1914), p.20192117</ispartof><rights>2019 The Author(s) 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c434t-76e88d66c461bb3e557746cfc6f3040836f937c4a4a8f65167a98a5b83b8868b3</citedby><cites>FETCH-LOGICAL-c434t-76e88d66c461bb3e557746cfc6f3040836f937c4a4a8f65167a98a5b83b8868b3</cites><orcidid>0000-0001-8210-2921 ; 0000-0002-4614-0338 ; 0000-0001-7470-8157 ; 0000-0001-6936-1697</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823055/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823055/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31662085$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Martinez, Julien</creatorcontrib><creatorcontrib>Bruner-Montero, Gaspar</creatorcontrib><creatorcontrib>Arunkumar, Ramesh</creatorcontrib><creatorcontrib>Smith, Sophia C L</creatorcontrib><creatorcontrib>Day, Jonathan P</creatorcontrib><creatorcontrib>Longdon, Ben</creatorcontrib><creatorcontrib>Jiggins, Francis M</creatorcontrib><title>Virus evolution in Wolbachia- infected Drosophila</title><title>Proceedings of the Royal Society. B, Biological sciences</title><addtitle>Proc Biol Sci</addtitle><description>, a common vertically transmitted symbiont, can protect insects against viral infection and prevent mosquitoes from transmitting viral pathogens. For this reason,
infected mosquitoes are being released to prevent the transmission of dengue and other arboviruses. An important question for the long-term success of these programmes is whether viruses can evolve to escape the antiviral effects of
We have found that
altered the outcome of competition between strains of the DCV virus in
However,
still effectively blocked the virus genotypes that were favoured in the presence of the symbiont. We conclude that
did cause an evolutionary response in viruses, but this has little or no impact on the effectiveness of virus blocking.</description><subject>Aedes</subject><subject>Animals</subject><subject>Culicidae</subject><subject>Drosophila - microbiology</subject><subject>Drosophila - physiology</subject><subject>Evolution</subject><subject>Symbiosis</subject><subject>Virus Diseases</subject><subject>Viruses</subject><subject>Wolbachia - physiology</subject><issn>0962-8452</issn><issn>1471-2954</issn><issn>1471-2954</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkElPwzAQhS0EoqVw5Yhy5JLg3c4FCZVVqsSF5WjZrkON0jjYSSX-PYlaKjiNRvPmzZsPgHMECwRLeRVTawoMUVlghMQBmCIqUI5LRg_BFJYc55IyPAEnKX1CCEsm2TGYEMQ5hpJNAXrzsU-Z24S673xoMt9k76E22q68zoeucrZzy-w2hhTala_1KTiqdJ3c2a7OwOv93cv8MV88PzzNbxa5pYR2ueBOyiXnlnJkDHGMCUG5rSyvCKRQEl6VRFiqqZYVZ4gLXUrNjCRGSi4NmYHrrW_bm7VbWtd0UdeqjX6t47cK2qv_k8av1EfYKC4xgYwNBpc7gxi-epc6tfbJurrWjQt9UpggyJmAjAzSYiu1w5spump_BkE1clYjZzVyViPnYeHib7i9_Bcs-QFOwnlW</recordid><startdate>20191106</startdate><enddate>20191106</enddate><creator>Martinez, Julien</creator><creator>Bruner-Montero, Gaspar</creator><creator>Arunkumar, Ramesh</creator><creator>Smith, Sophia C L</creator><creator>Day, Jonathan P</creator><creator>Longdon, Ben</creator><creator>Jiggins, Francis M</creator><general>The Royal Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8210-2921</orcidid><orcidid>https://orcid.org/0000-0002-4614-0338</orcidid><orcidid>https://orcid.org/0000-0001-7470-8157</orcidid><orcidid>https://orcid.org/0000-0001-6936-1697</orcidid></search><sort><creationdate>20191106</creationdate><title>Virus evolution in Wolbachia- infected Drosophila</title><author>Martinez, Julien ; Bruner-Montero, Gaspar ; Arunkumar, Ramesh ; Smith, Sophia C L ; Day, Jonathan P ; Longdon, Ben ; Jiggins, Francis M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c434t-76e88d66c461bb3e557746cfc6f3040836f937c4a4a8f65167a98a5b83b8868b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Aedes</topic><topic>Animals</topic><topic>Culicidae</topic><topic>Drosophila - microbiology</topic><topic>Drosophila - physiology</topic><topic>Evolution</topic><topic>Symbiosis</topic><topic>Virus Diseases</topic><topic>Viruses</topic><topic>Wolbachia - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Martinez, Julien</creatorcontrib><creatorcontrib>Bruner-Montero, Gaspar</creatorcontrib><creatorcontrib>Arunkumar, Ramesh</creatorcontrib><creatorcontrib>Smith, Sophia C L</creatorcontrib><creatorcontrib>Day, Jonathan P</creatorcontrib><creatorcontrib>Longdon, Ben</creatorcontrib><creatorcontrib>Jiggins, Francis M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Proceedings of the Royal Society. B, Biological sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Martinez, Julien</au><au>Bruner-Montero, Gaspar</au><au>Arunkumar, Ramesh</au><au>Smith, Sophia C L</au><au>Day, Jonathan P</au><au>Longdon, Ben</au><au>Jiggins, Francis M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Virus evolution in Wolbachia- infected Drosophila</atitle><jtitle>Proceedings of the Royal Society. B, Biological sciences</jtitle><addtitle>Proc Biol Sci</addtitle><date>2019-11-06</date><risdate>2019</risdate><volume>286</volume><issue>1914</issue><spage>20192117</spage><pages>20192117-</pages><issn>0962-8452</issn><issn>1471-2954</issn><eissn>1471-2954</eissn><abstract>, a common vertically transmitted symbiont, can protect insects against viral infection and prevent mosquitoes from transmitting viral pathogens. For this reason,
infected mosquitoes are being released to prevent the transmission of dengue and other arboviruses. An important question for the long-term success of these programmes is whether viruses can evolve to escape the antiviral effects of
We have found that
altered the outcome of competition between strains of the DCV virus in
However,
still effectively blocked the virus genotypes that were favoured in the presence of the symbiont. We conclude that
did cause an evolutionary response in viruses, but this has little or no impact on the effectiveness of virus blocking.</abstract><cop>England</cop><pub>The Royal Society</pub><pmid>31662085</pmid><doi>10.1098/rspb.2019.2117</doi><orcidid>https://orcid.org/0000-0001-8210-2921</orcidid><orcidid>https://orcid.org/0000-0002-4614-0338</orcidid><orcidid>https://orcid.org/0000-0001-7470-8157</orcidid><orcidid>https://orcid.org/0000-0001-6936-1697</orcidid><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0962-8452 |
| ispartof | Proceedings of the Royal Society. B, Biological sciences, 2019-11, Vol.286 (1914), p.20192117 |
| issn | 0962-8452 1471-2954 1471-2954 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6823055 |
| source | MEDLINE; JSTOR Archive Collection A-Z Listing; PubMed Central |
| subjects | Aedes Animals Culicidae Drosophila - microbiology Drosophila - physiology Evolution Symbiosis Virus Diseases Viruses Wolbachia - physiology |
| title | Virus evolution in Wolbachia- infected Drosophila |
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