MicroRNA-146a-deficient mice develop immune complex glomerulonephritis

MicroRNAs (miRNAs) play an important role in the kidneys under physiological and pathological conditions, but their role in immune glomerulonephritis is unclear. miR-146a has been identified as a key player in innate immunity and inflammatory responses, and in the kidney, this miRNA is involved in t...

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Veröffentlicht in:	Scientific reports 2019-10, Vol.9 (1), p.15597-13, Article 15597
Hauptverfasser:	Amrouche, Lucile, You, Sylvaine, Sauvaget, Virginia, Manda, Victoria, Lamarthée, Baptiste, Desbuissons, Geoffroy, Tinel, Claire, Rabant, Marion, Nguyen, Clément, Isnard, Pierre, Burtin, Martine, Charles, Nicolas, Legendre, Christophe, Terzi, Fabiola, Anglicheau, Dany
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/31 13/51 631/250/256/2515 631/80/304 64/60 96/21 Aging Animals Antigen-Antibody Complex - immunology Autoimmunity B-Lymphocytes, Regulatory - metabolism Biomarkers - metabolism Gene Expression Regulation Glomerulonephritis Glomerulonephritis - genetics Glomerulonephritis - immunology Glomerulonephritis - metabolism Hepatitis A Virus Cellular Receptor 1 - metabolism Homeostasis Humanities and Social Sciences Immunological memory Inflammation Innate immunity Interleukin 10 Kidneys Lymphocytes B Memory cells Mice MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA multidisciplinary Phenotype Phenotypes Science Science (multidisciplinary)
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