Simplify: A Mass Spectrometry Metabolomics Approach to Identify Additives and Synergists from Complex Mixtures

In fields ranging from environmental toxicology to drug discovery, it is critical to identify how multiple chemical compounds interact to perturb biological systems. Isolation-based approaches fail to incorporate multiconstituent interactions, such as synergy. We have developed an approach called “S...

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Veröffentlicht in:	Analytical chemistry (Washington) 2019-09, Vol.91 (17), p.11297-11305
Hauptverfasser:	Caesar, Lindsay K, Nogo, Sabina, Naphen, Cassandra N, Cech, Nadja B
Format:	Artikel
Sprache:	eng
Schlagworte:	Additives Antimicrobial activity Biological effects Chemical compounds Chemistry Constituents Mass spectrometry Mass spectroscopy Metabolomics Natural products Organic chemistry Salvia miltiorrhiza Synergists Toxicology Workflow
Online-Zugang:	Volltext
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