Antibody-mediated protection against Ebola virus

Recent Ebola virus disease epidemics have highlighted the need for effective vaccines and therapeutics to prevent future outbreaks. Antibodies are clearly critical for control of this deadly disease; however, the specific mechanisms of action of protective antibodies have yet to be defined. In this...

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Veröffentlicht in:	Nature immunology 2018-11, Vol.19 (11), p.1169-1178
Hauptverfasser:	Saphire, Erica Ollmann, Schendel, Sharon L., Gunn, Bronwyn M., Milligan, Jacob C., Alter, Galit
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/2152/2153/1291 631/250/255/2514 Animal models Antibodies Biomedical and Life Sciences Biomedicine Ebola hemorrhagic fever Ebola virus Ebolavirus Epidemics Immune clearance Immune system Immunoglobulins Immunology Immunotherapy Infection Infectious Diseases Marburg virus disease Neutralization Outbreaks Perspective Prevention Therapeutics Vaccination Vaccines Virus diseases
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