First-in-Human Phase 1 Study To Assess Safety, Tolerability, and Pharmacokinetics of a Novel Antifungal Drug, VL-2397, in Healthy Adults

VL-2397 is an antifungal drug with a novel mechanism of action, rapid fungicidal activity, and potent activity against , including azole-resistant strains. VL2397-101, a phase 1 first-in-human, randomized, double-blind, placebo-controlled dose-escalation study, was conducted in healthy adults to det...

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Veröffentlicht in:Antimicrobial agents and chemotherapy 2019-11, Vol.63 (11)
Hauptverfasser: Mammen, Mammen P, Armas, Danielle, Hughes, Frank H, Hopkins, Andrew M, Fisher, Cindy L, Resch, Pamela A, Rusalov, Denis, Sullivan, Sean M, Smith, Larry R
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Sprache:eng
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