Role of cardiac troponin I in the evaluation of myocardial injury

Role of cardiac troponin I in the evaluation of myocardial injury

Cardiac troponin I (cTnI) is highly specific for cardiac muscle. In this study, we compared the utility of CK and CK‐MB index versus cTnI in the assessment of myocardial infarction in 155 patients being evaluated for myocardial damage. As a cardiac marker for MI, Troponin I seems to be superior to C...

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Veröffentlicht in:Journal of clinical laboratory analysis 1998, Vol.12 (5), p.276-279
Hauptverfasser: Bhagavan, Nadhipuram V., Goldstein, Alan P., Honda, Stacey A. A., Uyehara, Jane, Blaisdell, Jodi, Sugiyama, Cheryl, Murakami, Lourna, Kang, Lucille, Fujitani, Gale
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers - blood
cardiac ischemia
cardiac markers
Creatine Kinase - blood
Humans
Isoenzymes
Kidney Failure, Chronic - blood
L-Lactate Dehydrogenase - blood
LDH
Myocardial Ischemia - blood
Myocardial Ischemia - diagnosis
Original
renal disease
Retrospective Studies
ROC Curve
troponin I
Troponin I - blood
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Zusammenfassung:Cardiac troponin I (cTnI) is highly specific for cardiac muscle. In this study, we compared the utility of CK and CK‐MB index versus cTnI in the assessment of myocardial infarction in 155 patients being evaluated for myocardial damage. As a cardiac marker for MI, Troponin I seems to be superior to CK‐MB. In the subset of patients with renal disease, cTnI has definite advantages over CK‐MB. In addition, the use of cTnI has the potential to replace the measurement of lactate dehydrogenase isoenzymes. J. Clin. Lab. Anal. 12:276–279, 1998. © 1998 Wiley‐Liss, Inc.
ISSN:0887-8013
1098-2825
DOI:10.1002/(SICI)1098-2825(1998)12:5<276::AID-JCLA4>3.0.CO;2-4