Concurrent bariatric surgery and surgical resection of massive localized lymphedema of the thigh. A case report

Massive localised lymphedema (MLL) is considered a rare large, pendulous localised benign overgrowth of lymphoproliferative tissue commonly seen in patients with morbid obesity. Histologically, it may be mistaken for well-differentiated liposarcoma; hence, it is also known as pseudosarcoma. We descr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Annals of medicine and surgery 2019-11, Vol.47, p.53-56
Hauptverfasser: Hou, Loo Guo, Prabakaran, Anusha, Rajan, Reynu, Mohd Nor, Fatimah Binti, Ritza Kosai, Nik
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 56
container_issue
container_start_page 53
container_title Annals of medicine and surgery
container_volume 47
creator Hou, Loo Guo
Prabakaran, Anusha
Rajan, Reynu
Mohd Nor, Fatimah Binti
Ritza Kosai, Nik
description Massive localised lymphedema (MLL) is considered a rare large, pendulous localised benign overgrowth of lymphoproliferative tissue commonly seen in patients with morbid obesity. Histologically, it may be mistaken for well-differentiated liposarcoma; hence, it is also known as pseudosarcoma. We describe the successful management of MLL of the left medial thigh in a 35-year-old man weighing 220 kgs (BMI 80.8 kgs/m2). He underwent a concurrent laparoscopic sleeve gastrectomy with surgical resection of the MLL. He recovered well and during our last follow up six months after the operation, he is ambulating well and weighs 148 kgs (BMI 54.4 kgs/m2). MLL is a form of secondary lymphedema resulting in disruption or compression of normal lymphatic drainage due to fat accumulation in obese patients. Patients usually delay treatment for even up to a decade, when it becomes sufficiently large enough to restrict mobility and daily activities, or when it becomes infected. MLL is primarily a clinical diagnosis. A detailed history regarding its slow growth spanning over the years makes malignancy less likely. However, if left untreated, MLL may progress to angiosarcoma. Imaging studies such as computed tomography (CT) and a Magnetic Resonance Imaging (MRI) are usually performed to rule out malignancy or vascular malformations. A tissue biopsy is not recommended unless there are suspicious pigmented lesions. MLL remains to be underdiagnosed. Due to the obesity epidemic, clinicians must be aware of this once rare disease. The role of concurrent bariatric surgery with surgical resection of MLL warrants further studies. •Massive localised lymphedema is a rare, benign overgrowth of lymphoproliferative tissue commonly associated with obesity.•Patients usually delay seeking treatment until it affects their daily activities, or when it becomes infected.•A tissue biopsy is not recommended unless there are suspicious pigmented lesions.•MLL remains to be underdiagnosed. Due to the obesity epidemic, it is essential that clinicians be aware of this disease.•The role of concurrent bariatric surgery with surgical resection of MLL warrants further studies.
doi_str_mv 10.1016/j.amsu.2019.10.002
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6806377</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S2049080119301359</els_id><sourcerecordid>2312268135</sourcerecordid><originalsourceid>FETCH-LOGICAL-c406t-8ee79ff8ad6d65a689b32bf33fdefc5d3e66aa6dcd419e83b069b9931cfb40723</originalsourceid><addsrcrecordid>eNp9kUtrGzEUhUVJaUKaP9BF0TIbT_WwNRoIgWD6gkA37Vrcka5smZmRK80YnF8fTe2GdNOF0OWec48eHyEfOKs44-rTroI-T5VgvCmNijHxhlwJtmwWTDN-8aq-JDc57xhjnK2kUvoduZRc6ZpLeUXiOg52SgmHkbaQAowpWJqntMF0pDC4P3Ww0NGEGe0Y4kCjpz3kHA5Iu1ik8ISOdsd-v0WHPcz6uMWywmZb0QdqIWMZ38c0vidvPXQZb877Nfn15fPP9bfF44-v39cPjwu7ZGpcaMS68V6DU06tQOmmlaL1UnqH3q6cRKUAlLNuyRvUsmWqaZtGcuvbJauFvCb3p9z91PbobHlfgs7sU-ghHU2EYP5VhrA1m3gwSjMl67oE3J4DUvw9YR5NH7LFroMB45SNkFwIpblcFas4WW2KOSf0L8dwZmZYZmdmWGaGNfcKrDL08fUFX0b-oimGu5MByzcdAiaTbcDBogupcDAuhv_lPwPWg6lm</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2312268135</pqid></control><display><type>article</type><title>Concurrent bariatric surgery and surgical resection of massive localized lymphedema of the thigh. A case report</title><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Hou, Loo Guo ; Prabakaran, Anusha ; Rajan, Reynu ; Mohd Nor, Fatimah Binti ; Ritza Kosai, Nik</creator><creatorcontrib>Hou, Loo Guo ; Prabakaran, Anusha ; Rajan, Reynu ; Mohd Nor, Fatimah Binti ; Ritza Kosai, Nik</creatorcontrib><description>Massive localised lymphedema (MLL) is considered a rare large, pendulous localised benign overgrowth of lymphoproliferative tissue commonly seen in patients with morbid obesity. Histologically, it may be mistaken for well-differentiated liposarcoma; hence, it is also known as pseudosarcoma. We describe the successful management of MLL of the left medial thigh in a 35-year-old man weighing 220 kgs (BMI 80.8 kgs/m2). He underwent a concurrent laparoscopic sleeve gastrectomy with surgical resection of the MLL. He recovered well and during our last follow up six months after the operation, he is ambulating well and weighs 148 kgs (BMI 54.4 kgs/m2). MLL is a form of secondary lymphedema resulting in disruption or compression of normal lymphatic drainage due to fat accumulation in obese patients. Patients usually delay treatment for even up to a decade, when it becomes sufficiently large enough to restrict mobility and daily activities, or when it becomes infected. MLL is primarily a clinical diagnosis. A detailed history regarding its slow growth spanning over the years makes malignancy less likely. However, if left untreated, MLL may progress to angiosarcoma. Imaging studies such as computed tomography (CT) and a Magnetic Resonance Imaging (MRI) are usually performed to rule out malignancy or vascular malformations. A tissue biopsy is not recommended unless there are suspicious pigmented lesions. MLL remains to be underdiagnosed. Due to the obesity epidemic, clinicians must be aware of this once rare disease. The role of concurrent bariatric surgery with surgical resection of MLL warrants further studies. •Massive localised lymphedema is a rare, benign overgrowth of lymphoproliferative tissue commonly associated with obesity.•Patients usually delay seeking treatment until it affects their daily activities, or when it becomes infected.•A tissue biopsy is not recommended unless there are suspicious pigmented lesions.•MLL remains to be underdiagnosed. Due to the obesity epidemic, it is essential that clinicians be aware of this disease.•The role of concurrent bariatric surgery with surgical resection of MLL warrants further studies.</description><identifier>ISSN: 2049-0801</identifier><identifier>EISSN: 2049-0801</identifier><identifier>DOI: 10.1016/j.amsu.2019.10.002</identifier><identifier>PMID: 31687133</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>MLL ; Morbid obesity ; Original Research ; Pseudosarcoma ; Sleeve gastrectomy ; Surgical resection</subject><ispartof>Annals of medicine and surgery, 2019-11, Vol.47, p.53-56</ispartof><rights>2019 The Author(s)</rights><rights>2019 The Author(s).</rights><rights>2019 The Author(s) 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c406t-8ee79ff8ad6d65a689b32bf33fdefc5d3e66aa6dcd419e83b069b9931cfb40723</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806377/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806377/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31687133$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hou, Loo Guo</creatorcontrib><creatorcontrib>Prabakaran, Anusha</creatorcontrib><creatorcontrib>Rajan, Reynu</creatorcontrib><creatorcontrib>Mohd Nor, Fatimah Binti</creatorcontrib><creatorcontrib>Ritza Kosai, Nik</creatorcontrib><title>Concurrent bariatric surgery and surgical resection of massive localized lymphedema of the thigh. A case report</title><title>Annals of medicine and surgery</title><addtitle>Ann Med Surg (Lond)</addtitle><description>Massive localised lymphedema (MLL) is considered a rare large, pendulous localised benign overgrowth of lymphoproliferative tissue commonly seen in patients with morbid obesity. Histologically, it may be mistaken for well-differentiated liposarcoma; hence, it is also known as pseudosarcoma. We describe the successful management of MLL of the left medial thigh in a 35-year-old man weighing 220 kgs (BMI 80.8 kgs/m2). He underwent a concurrent laparoscopic sleeve gastrectomy with surgical resection of the MLL. He recovered well and during our last follow up six months after the operation, he is ambulating well and weighs 148 kgs (BMI 54.4 kgs/m2). MLL is a form of secondary lymphedema resulting in disruption or compression of normal lymphatic drainage due to fat accumulation in obese patients. Patients usually delay treatment for even up to a decade, when it becomes sufficiently large enough to restrict mobility and daily activities, or when it becomes infected. MLL is primarily a clinical diagnosis. A detailed history regarding its slow growth spanning over the years makes malignancy less likely. However, if left untreated, MLL may progress to angiosarcoma. Imaging studies such as computed tomography (CT) and a Magnetic Resonance Imaging (MRI) are usually performed to rule out malignancy or vascular malformations. A tissue biopsy is not recommended unless there are suspicious pigmented lesions. MLL remains to be underdiagnosed. Due to the obesity epidemic, clinicians must be aware of this once rare disease. The role of concurrent bariatric surgery with surgical resection of MLL warrants further studies. •Massive localised lymphedema is a rare, benign overgrowth of lymphoproliferative tissue commonly associated with obesity.•Patients usually delay seeking treatment until it affects their daily activities, or when it becomes infected.•A tissue biopsy is not recommended unless there are suspicious pigmented lesions.•MLL remains to be underdiagnosed. Due to the obesity epidemic, it is essential that clinicians be aware of this disease.•The role of concurrent bariatric surgery with surgical resection of MLL warrants further studies.</description><subject>MLL</subject><subject>Morbid obesity</subject><subject>Original Research</subject><subject>Pseudosarcoma</subject><subject>Sleeve gastrectomy</subject><subject>Surgical resection</subject><issn>2049-0801</issn><issn>2049-0801</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp9kUtrGzEUhUVJaUKaP9BF0TIbT_WwNRoIgWD6gkA37Vrcka5smZmRK80YnF8fTe2GdNOF0OWec48eHyEfOKs44-rTroI-T5VgvCmNijHxhlwJtmwWTDN-8aq-JDc57xhjnK2kUvoduZRc6ZpLeUXiOg52SgmHkbaQAowpWJqntMF0pDC4P3Ww0NGEGe0Y4kCjpz3kHA5Iu1ik8ISOdsd-v0WHPcz6uMWywmZb0QdqIWMZ38c0vidvPXQZb877Nfn15fPP9bfF44-v39cPjwu7ZGpcaMS68V6DU06tQOmmlaL1UnqH3q6cRKUAlLNuyRvUsmWqaZtGcuvbJauFvCb3p9z91PbobHlfgs7sU-ghHU2EYP5VhrA1m3gwSjMl67oE3J4DUvw9YR5NH7LFroMB45SNkFwIpblcFas4WW2KOSf0L8dwZmZYZmdmWGaGNfcKrDL08fUFX0b-oimGu5MByzcdAiaTbcDBogupcDAuhv_lPwPWg6lm</recordid><startdate>20191101</startdate><enddate>20191101</enddate><creator>Hou, Loo Guo</creator><creator>Prabakaran, Anusha</creator><creator>Rajan, Reynu</creator><creator>Mohd Nor, Fatimah Binti</creator><creator>Ritza Kosai, Nik</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20191101</creationdate><title>Concurrent bariatric surgery and surgical resection of massive localized lymphedema of the thigh. A case report</title><author>Hou, Loo Guo ; Prabakaran, Anusha ; Rajan, Reynu ; Mohd Nor, Fatimah Binti ; Ritza Kosai, Nik</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c406t-8ee79ff8ad6d65a689b32bf33fdefc5d3e66aa6dcd419e83b069b9931cfb40723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>MLL</topic><topic>Morbid obesity</topic><topic>Original Research</topic><topic>Pseudosarcoma</topic><topic>Sleeve gastrectomy</topic><topic>Surgical resection</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hou, Loo Guo</creatorcontrib><creatorcontrib>Prabakaran, Anusha</creatorcontrib><creatorcontrib>Rajan, Reynu</creatorcontrib><creatorcontrib>Mohd Nor, Fatimah Binti</creatorcontrib><creatorcontrib>Ritza Kosai, Nik</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of medicine and surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hou, Loo Guo</au><au>Prabakaran, Anusha</au><au>Rajan, Reynu</au><au>Mohd Nor, Fatimah Binti</au><au>Ritza Kosai, Nik</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Concurrent bariatric surgery and surgical resection of massive localized lymphedema of the thigh. A case report</atitle><jtitle>Annals of medicine and surgery</jtitle><addtitle>Ann Med Surg (Lond)</addtitle><date>2019-11-01</date><risdate>2019</risdate><volume>47</volume><spage>53</spage><epage>56</epage><pages>53-56</pages><issn>2049-0801</issn><eissn>2049-0801</eissn><abstract>Massive localised lymphedema (MLL) is considered a rare large, pendulous localised benign overgrowth of lymphoproliferative tissue commonly seen in patients with morbid obesity. Histologically, it may be mistaken for well-differentiated liposarcoma; hence, it is also known as pseudosarcoma. We describe the successful management of MLL of the left medial thigh in a 35-year-old man weighing 220 kgs (BMI 80.8 kgs/m2). He underwent a concurrent laparoscopic sleeve gastrectomy with surgical resection of the MLL. He recovered well and during our last follow up six months after the operation, he is ambulating well and weighs 148 kgs (BMI 54.4 kgs/m2). MLL is a form of secondary lymphedema resulting in disruption or compression of normal lymphatic drainage due to fat accumulation in obese patients. Patients usually delay treatment for even up to a decade, when it becomes sufficiently large enough to restrict mobility and daily activities, or when it becomes infected. MLL is primarily a clinical diagnosis. A detailed history regarding its slow growth spanning over the years makes malignancy less likely. However, if left untreated, MLL may progress to angiosarcoma. Imaging studies such as computed tomography (CT) and a Magnetic Resonance Imaging (MRI) are usually performed to rule out malignancy or vascular malformations. A tissue biopsy is not recommended unless there are suspicious pigmented lesions. MLL remains to be underdiagnosed. Due to the obesity epidemic, clinicians must be aware of this once rare disease. The role of concurrent bariatric surgery with surgical resection of MLL warrants further studies. •Massive localised lymphedema is a rare, benign overgrowth of lymphoproliferative tissue commonly associated with obesity.•Patients usually delay seeking treatment until it affects their daily activities, or when it becomes infected.•A tissue biopsy is not recommended unless there are suspicious pigmented lesions.•MLL remains to be underdiagnosed. Due to the obesity epidemic, it is essential that clinicians be aware of this disease.•The role of concurrent bariatric surgery with surgical resection of MLL warrants further studies.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>31687133</pmid><doi>10.1016/j.amsu.2019.10.002</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2049-0801
ispartof Annals of medicine and surgery, 2019-11, Vol.47, p.53-56
issn 2049-0801
2049-0801
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6806377
source EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection
subjects MLL
Morbid obesity
Original Research
Pseudosarcoma
Sleeve gastrectomy
Surgical resection
title Concurrent bariatric surgery and surgical resection of massive localized lymphedema of the thigh. A case report
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T13%3A22%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Concurrent%20bariatric%20surgery%20and%20surgical%20resection%20of%20massive%20localized%20lymphedema%20of%20the%20thigh.%20A%20case%20report&rft.jtitle=Annals%20of%20medicine%20and%20surgery&rft.au=Hou,%20Loo%20Guo&rft.date=2019-11-01&rft.volume=47&rft.spage=53&rft.epage=56&rft.pages=53-56&rft.issn=2049-0801&rft.eissn=2049-0801&rft_id=info:doi/10.1016/j.amsu.2019.10.002&rft_dat=%3Cproquest_pubme%3E2312268135%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2312268135&rft_id=info:pmid/31687133&rft_els_id=S2049080119301359&rfr_iscdi=true