The Host Immune System Facilitates Disseminated Staphylococcus aureus Disease Due to Phagocytic Attraction to Candida albicans during Coinfection: a Case of Bait and Switch

Invasive infections account for 15 to 50% of fatal bloodstream infections annually. These disseminated infections often arise without a defined portal of entry into the host but cause high rates of mortality. The fungus and the Gram-positive bacterium can form polymicrobial biofilms on epithelial ti...

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Veröffentlicht in:	Infection and immunity 2019-11, Vol.87 (11)
Hauptverfasser:	Allison, Devon L, Scheres, Nina, Willems, Hubertine M E, Bode, Carolien S, Krom, Bastiaan P, Shirtliff, Mark E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Candida albicans Candidiasis - immunology Candidiasis - microbiology Cell Line Coinfection Host-Associated Microbial Communities Immunity, Innate Macrophages - physiology Mice Phagocytosis Staphylococcal Infections - immunology Staphylococcal Infections - microbiology Staphylococcus aureus
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