Proximity Labeling To Map Host-Pathogen Interactions at the Membrane of a Bacterium-Containing Vacuole in Chlamydia trachomatis-Infected Human Cells

Many intracellular bacteria, including the obligate intracellular pathogen , grow within a membrane-bound bacterium-containing vacuole (BCV). Secreted cytosolic effectors modulate host activity, but an understanding of the host-pathogen interactions that occur at the BCV membrane is limited by the d...

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Veröffentlicht in:	Infection and immunity 2019-11, Vol.87 (11)
Hauptverfasser:	Olson, Macy G, Widner, Ray E, Jorgenson, Lisa M, Lawrence, Alyssa, Lagundzin, Dragana, Woods, Nicholas T, Ouellette, Scot P, Rucks, Elizabeth A
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins Biotinylation Cellular Microbiology: Pathogen-Host Cell Molecular Interactions Chlamydia trachomatis - genetics Chlamydia trachomatis - physiology Chlamydia trachomatis - ultrastructure Gene Expression Regulation, Bacterial HeLa Cells Humans Mass Spectrometry Membrane Proteins - genetics Membrane Proteins - metabolism Recombinant Proteins Streptavidin
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