Nerve Growth Factor Accelerates Seizure Development, Enhances Mossy Fiber Sprouting, and Attenuates Seizure-Induced Decreases in Neuronal Density in the Kindling Model of Epilepsy

Recurrent seizure activity induced during kindling has been reported to produce a functional synaptic reorganization of the mossy fibers in the hippocampus. To date, it is unclear whether this kindling-induced growth is secondary to decreases in hilar neuron density, which are presumed to reflect hi...

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Veröffentlicht in:	The Journal of neuroscience 1997-07, Vol.17 (14), p.5288-5296
Hauptverfasser:	Adams, Beth, Sazgar, Mona, Osehobo, Philip, Van der Zee, Catharina E. E. M, Diamond, Jack, Fahnestock, Margaret, Racine, Ronald J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Count - drug effects Disease Models, Animal Epilepsy - chemically induced Kindling, Neurologic - physiology Male Nerve Growth Factors - pharmacology Nerve Regeneration - drug effects Rats
Online-Zugang:	Volltext
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