Molecular recognition of ubiquitin and Lys63-linked diubiquitin by STAM2 UIM-SH3 dual domain: the effect of its linker length and flexibility

Multidomain proteins represent a broad spectrum of the protein landscape and are involved in various interactions. They could be considered as modular building blocks assembled in distinct fashion and connected by linkers of varying lengths and sequences. Due to their intrinsic flexibility, these li...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2019-10, Vol.9 (1), p.14645-12, Article 14645
Hauptverfasser:	Nguyen, Minh-Ha, Martin, Marie, Kim, Henry, Gabel, Frank, Walker, Olivier, Hologne, Maggy
Format:	Artikel
Sprache:	eng
Schlagworte:	101/6 140/131 631/535/1261 631/535/878/1263 Adaptor Proteins, Signal Transducing - metabolism Analytical chemistry Biochemistry, Molecular Biology Chemical Sciences Endosomal Sorting Complexes Required for Transport - metabolism Endosomal Sorting Complexes Required for Transport - ultrastructure Flexibility Humanities and Social Sciences Life Sciences Molecular Dynamics Simulation multidisciplinary Nuclear Magnetic Resonance, Biomolecular Protein Binding Protein structure Scattering, Small Angle Science Science (multidisciplinary) src Homology Domains Tumbling Ubiquitin Ubiquitins - metabolism Ubiquitins - ultrastructure X-Ray Diffraction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!