Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice

The pathogenesis of Alzheimer's disease (AD) is characterized by both accumulation of β-amyloid (Aβ) plaque and formation of neurofibrillary tangles in the brain. Recent evidence shows that autophagy activation may potently promote intracellular Aβ clearance. Thus targeting autophagy becomes a...

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Veröffentlicht in:Acta pharmacologica Sinica 2019-10, Vol.40 (10), p.1279-1291
Hauptverfasser: Fan, Lei, Qiu, Xiao-xia, Zhu, Zhi-yuan, Lv, Jian-lu, Lu, Jian, Mao, Fei, Zhu, Jin, Wang, Jia-ying, Guan, Xiao-wei, Chen, Jing, Ren, Jin, Ye, Ji-ming, Zhao, Yong-hua, Li, Jian, Shen, Xu
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Sprache:eng
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