Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
The pathogenesis of Alzheimer's disease (AD) is characterized by both accumulation of β-amyloid (Aβ) plaque and formation of neurofibrillary tangles in the brain. Recent evidence shows that autophagy activation may potently promote intracellular Aβ clearance. Thus targeting autophagy becomes a...
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Veröffentlicht in: | Acta pharmacologica Sinica 2019-10, Vol.40 (10), p.1279-1291 |
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Hauptverfasser: | , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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