Workflow for defining reference chemicals for assessing performance of in vitro assays

Instilling confidence in use of in vitro assays for predictive toxicology requires evaluation of assay performance. Performance is typically assessed using reference chemicals--compounds with defined activity against the test system target. However, developing reference chemical lists has historical...

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Veröffentlicht in:	ALTEX, alternatives to animal experimentation alternatives to animal experimentation, 2019-01, Vol.36 (2), p.261-276
Hauptverfasser:	Judson, Richard S, Thomas, Russell S, Baker, Nancy, Simha, Anita, Howey, Xia Meng, Marable, Carmen, Kleinstreuer, Nicole C, Houck, Keith A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anopheles Assaying Biological Assay Chemicals Databases, Factual Hazardous Substances - metabolism Hazardous Substances - toxicity High-Throughput Screening Assays - methods Humans In Vitro Techniques - methods In Vitro Techniques - standards Methods Properties Toxicology Workflow Workflow software
Online-Zugang:	Volltext
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