NMDAR activation regulates the daily rhythms of sleep and mood

The present studies examine the effects of NMDAR activation by NYX-2925 diurnal rhythmicity of both sleep and wake as well as emotion. Twenty-four-hour sleep EEG recordings were obtained in sleep-deprived and non-sleep-deprived rats. In addition, the day-night cycle of both activity and mood was mea...

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Veröffentlicht in:	Sleep (New York, N.Y.) N.Y.), 2019-10, Vol.42 (10), p.1
Hauptverfasser:	Burgdorf, Jeffrey S, Vitaterna, Martha H, Olker, Christopher J, Song, Eun Joo, Christian, Edward P, Sørensen, Laurits, Turek, Fred W, Madsen, Torsten M, Khan, M Amin, Kroes, Roger A, Moskal, Joseph R
Format:	Artikel
Sprache:	eng
Schlagworte:	Affect - drug effects Affect - physiology Animals Basic Science of Sleep and Circadian Rhythms Circadian Rhythm - drug effects Circadian Rhythm - physiology Electroencephalography Electroencephalography - methods Male NREM sleep Rats Rats, Sprague-Dawley Receptors, N-Methyl-D-Aspartate - agonists Receptors, N-Methyl-D-Aspartate - physiology REM sleep Sleep - drug effects Sleep - physiology Sleep deprivation Sleep Deprivation - drug therapy Sleep Deprivation - physiopathology Spiro Compounds - pharmacology Spiro Compounds - therapeutic use Wakefulness - drug effects Wakefulness - physiology
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