MYCN-mediated regulation of the HES1 promoter enhances the chemoresistance of small-cell lung cancer by modulating apoptosis

MYCN, a member of the MYC family, is correlated with tumorigenesis, metastasis and therapy in many malignancies; however, its role in small-cell lung cancer (SCLC) remains unclear. In this study, we sought to identify the function of MYCN in SCLC chemoresistance and found that MYCN is overexpressed...

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Veröffentlicht in:	American journal of cancer research 2019-01, Vol.9 (9), p.1938-1956
Hauptverfasser:	Tong, Qin, Ouyang, Shuming, Chen, Rui, Huang, Jie, Guo, Linlang
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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