Kappa opioid receptor agonists improve postoperative cognitive dysfunction in rats via the JAK2/STAT3 signaling pathway

Postoperative cognitive dysfunction (POCD) is a common and well-known complication following surgery, particularly cardiopulmonary bypass (CPB) surgery. There are currently no suitable treatments for POCD, which is associated with increased illness and mortality rates. The present study aimed to ide...

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Veröffentlicht in:	International journal of molecular medicine 2019-11, Vol.44 (5), p.1866-1876
Hauptverfasser:	Li, Xi, Sun, Yingjie, Jin, Qiang, Song, Dandan, Diao, Yugang
Format:	Artikel
Sprache:	eng
Schlagworte:	Agricultural associations Animal cognition Apoptosis Brain damage Brain injuries Cognitive disorders Coronary artery bypass Enzyme-linked immunosorbent assay Fluorescent antibody technique Health aspects Heart surgery Intubation Ischemia Kinases Laboratory animals Narcotics Nervous system Neurons Novels Oxidative stress Pharmaceuticals Phosphorylation Proteins Rodents Studies Veins & arteries Water
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