Intraocular Metastasis in Unilateral Multifocal Uveal Melanoma Without Melanocytosis or Germline BAP1 Mutations

IMPORTANCE: There has been speculation on the pathogenesis of unilateral multifocal uveal melanoma, but there remains no convincing explanation. Genetic analysis suggests that unilateral multifocal uveal melanoma may represent intraocular metastasis with increased risk of systemic metastasis. OBJECT...

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Veröffentlicht in:	Archives of ophthalmology (1960) 2019-12, Vol.137 (12), p.1434-1439
Hauptverfasser:	Durante, Michael A, Walter, Scott D, Paez-Escamilla, Manuel, Tokarev, Julian, Decatur, Christina L, Dubovy, Sander R, Schefler, Amy C, Harbour, J. William
Format:	Artikel
Sprache:	eng
Schlagworte:	Brachytherapy BRCA1 protein Brief Report Comments DNA sequencing Eye Gene expression Genetic analysis Melanoma Metastases Metastasis Mutation Oncology Online First Pathogenesis Tumors
Online-Zugang:	Volltext
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