Polyacetate and Polycarbonate RNA: Acylating Reagents and Properties

Acylation of RNA at 2′-OH groups is widely applied in mapping RNA structure and recently for controlling RNA function. Reactions are described that install the smallest 2-carbon acyl groups on RNAnamely, 2′-O-acetyl and 2′-O-carbonate groups. Hybridization and thermal melting experiments are perfor...

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Veröffentlicht in:	Organic letters 2019-07, Vol.21 (14), p.5413-5416
Hauptverfasser:	Habibian, Maryam, Velema, Willem A, Kietrys, Anna M, Onishi, Yoshiyuki, Kool, Eric T
Format:	Artikel
Sprache:	eng
Schlagworte:	acylation melting moieties organic compounds RNA RNA-directed DNA polymerase
Online-Zugang:	Volltext
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