In Utero Cocaine-Induced Dysfunction of Dopamine D1 Receptor Signaling And Abnormal Differentiation of Cerebral Cortical Neurons

Monoamines modulate neuronal differentiation, and alteration of monoamine neurotransmission during development produces specific changes in neuronal structure, function, and pattern formation. We have previously observed that prenatal exposure to cocaine in a clinically relevant animal model produce...

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Veröffentlicht in:	The Journal of neuroscience 2000-06, Vol.20 (12), p.4606-4614
Hauptverfasser:	Jones, Liesl B, Stanwood, Gregg D, Reinoso, Blesilda S, Washington, Ricardo A, Wang, Hoau-Yan, Friedman, Eitan, Levitt, Pat
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Cerebral Cortex - drug effects Cerebral Cortex - embryology Cerebral Cortex - growth & development Cocaine - toxicity Dendrites - drug effects Dendrites - physiology Dendrites - ultrastructure Embryonic and Fetal Development Female GTP-Binding Protein alpha Subunits, Gs - metabolism Gyrus Cinguli - drug effects Gyrus Cinguli - embryology Gyrus Cinguli - growth & development Neurons - cytology Neurons - drug effects Neurons - physiology Pregnancy Prenatal Exposure Delayed Effects Pyramidal Cells - cytology Pyramidal Cells - drug effects Pyramidal Cells - physiology Rabbits Receptors, Dopamine D1 - drug effects Receptors, Dopamine D1 - physiology Signal Transduction
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