Targeted deep sequencing of urothelial bladder cancers and associated urinary DNA: a 23‐gene panel with utility for non‐invasive diagnosis and risk stratification

Objectives To develop a focused panel of somatic mutations (SMs) present in the majority of urothelial bladder cancers (UBCs), to investigate the diagnostic and prognostic utility of this panel, and to compare the identification of SMs in urinary cell‐pellet (cp)DNA and cell‐free (cf)DNA as part of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BJU international 2019-09, Vol.124 (3), p.532-544
Hauptverfasser:	Ward, Douglas G., Gordon, Naheema S., Boucher, Rebecca H., Pirrie, Sarah J., Baxter, Laura, Ott, Sascha, Silcock, Lee, Whalley, Celina M., Stockton, Joanne D., Beggs, Andrew D., Griffiths, Mike, Abbotts, Ben, Ijakipour, Hanieh, Latheef, Fathimath N., Robinson, Robert A., White, Andrew J., James, Nicholas D., Zeegers, Maurice P., Cheng, K. K., Bryan, Richard T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over AKT1 protein Bladder cancer BladderCancer blcsm Cdc4 protein Databases, Genetic Deoxyribonucleic acid detection Diagnosis DNA DNA sequencing DNA, Neoplasm - urine ErbB-2 protein ErbB-3 protein Female Fibroblast growth factor receptors Gene frequency High-Throughput Nucleotide Sequencing - methods Humans Male Middle Aged Mutation Mutation - genetics mutations p53 Protein Prognosis Retinoid X receptor α Risk Assessment Sequence Analysis, DNA Translational Science Tumors Urinary Bladder Neoplasms - diagnosis Urinary Bladder Neoplasms - genetics Urine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!