Mechanisms of Small Heat Shock Proteins

Small heat shock proteins (sHSPs) are ATP-independent chaperones that delay formation of harmful protein aggregates. sHSPs' role in protein homeostasis has been appreciated for decades, but their mechanisms of action remain poorly understood. This gap in understanding is largely a consequence o...

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Veröffentlicht in:	Cold Spring Harbor perspectives in biology 2019-10, Vol.11 (10), p.a034025
Hauptverfasser:	Janowska, Maria K, Baughman, Hannah E R, Woods, Christopher N, Klevit, Rachel E
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis Chaperones Heat shock proteins Homeostasis Metal ions Oxidation PERSPECTIVES Phosphorylation Proteins Small heat shock proteins
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