Red Wine Grape Pomace Attenuates Atherosclerosis and Myocardial Damage and Increases Survival in Association with Improved Plasma Antioxidant Activity in a Murine Model of Lethal Ischemic Heart Disease

A healthy dietary pattern and high quality nutrient intake reduce atherosclerotic cardiovascular disease risk. Red wine grape pomace (RWGP)-a rich natural source of dietary fiber and antioxidants-appears to be a potential functional food ingredient. The impact of a dietary supplementation with RWGP...

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Veröffentlicht in:	Nutrients 2019-09, Vol.11 (9), p.2135
Hauptverfasser:	Rivera, Katherine, Salas-Pérez, Francisca, Echeverría, Guadalupe, Urquiaga, Inés, Dicenta, Sara, Pérez, Druso, de la Cerda, Paula, González, Leticia, Andia, Marcelo E, Uribe, Sergio, Tejos, Cristián, Martínez, Gonzalo, Busso, Dolores, Irarrázaval, Pablo, Rigotti, Attilio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Feed Animal models Animals Anthocyanins Anti-inflammatory agents antioxidant activity Antioxidants Antioxidants - administration & dosage Antioxidants - isolation & purification Antioxidants - metabolism Aorta - metabolism Aorta - pathology Aortic Diseases - blood Aortic Diseases - genetics Aortic Diseases - pathology Aortic Diseases - prevention & control Arteriosclerosis Atherosclerosis Atherosclerosis - blood Atherosclerosis - genetics Atherosclerosis - pathology Atherosclerosis - prevention & control Biomarkers - blood blood lipids Cardiovascular disease Cardiovascular diseases Catechin Cholesterol cholic acid Chronic illnesses Coronary artery disease coronary disease death Diet Diet, Atherogenic Dietary fiber Dietary Supplements Disease Models, Animal Drinking behavior eating habits Electrical engineering Female flour Fruit - chemistry functional foods grape pomace Grapes Heart attacks Heart diseases histology Hypertension IL-1β Inflammation Inflammation Mediators - blood Inflammatory response ingredients interleukin-10 Interleukin-10 - blood Ischemia Laboratory animals Lipid peroxidation Lipids Lipids - blood Lipopolysaccharides Lipoproteins Low density lipoprotein magnetic resonance imaging Male Medicine mice Mice, Knockout, ApoE Microglia Mortality myocardial infarction Myocardial Ischemia - blood Myocardial Ischemia - genetics Myocardial Ischemia - pathology Myocardial Ischemia - prevention & control Myocardium - metabolism Myocardium - pathology nutrient intake Nutrition research oats Oxidation Oxidative Stress Peroxidation Plant Extracts - administration & dosage Plant Extracts - blood Plant Extracts - isolation & purification Plaque, Atherosclerotic Plasma levels Polyphenols red wines Scavenger Receptors, Class B - deficiency Scavenger Receptors, Class B - genetics Seeds Skin Statins therapeutics tumor necrosis factor-alpha Tumor Necrosis Factor-alpha - blood Tumor necrosis factor-α Vitis - chemistry wine grapes Wines
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