Chemoresistance in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC), generally known as pancreatic cancer (PC), ranks the fourth leading cause of cancer-related deaths in the western world. While the incidence of pancreatic cancer is displaying a rising tendency every year, the mortality rate has not decreased significantly be...

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Veröffentlicht in:	International journal of molecular sciences 2019-09, Vol.20 (18), p.4504
Hauptverfasser:	Zeng, Siyuan, Pöttler, Marina, Lan, Bin, Grützmann, Robert, Pilarsky, Christian, Yang, Hai
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Animals Apoptosis Biomarkers Cancer therapies Cell adhesion & migration Cell cycle Chemoresistance Chemotherapy Deoxycytidine - analogs & derivatives Deoxycytidine - chemistry Deoxycytidine - pharmacology Deoxycytidine - therapeutic use Deoxyribonucleic acid DNA DNA repair Drug resistance Drug Resistance, Neoplasm - drug effects Drug Resistance, Neoplasm - genetics Enzymes Epithelial cells Gemcitabine Genome Growth inhibition Humans Kinases Medical prognosis Metabolism Metabolites Metastasis Nucleosides Pancreatic cancer Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology Pancreatic Neoplasms - therapy Phosphorylation Review Transport Treatment Outcome Tumor Microenvironment - drug effects
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