PTEN, A Target of Microrna-374b, Contributes to the Radiosensitivity of Canine Oral Melanoma Cells

Canine oral malignant melanoma (CoMM) is often treated by radiation therapy in veterinary medicine. However, not all cases are successfully managed by this treatment. For improved efficacy of radiation therapy, biomarkers predicting the radiosensitivity of melanoma cells need to be explored. Here, w...

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Veröffentlicht in:	International journal of molecular sciences 2019-09, Vol.20 (18), p.4631
Hauptverfasser:	Noguchi, Shunsuke, Ogusu, Ryo, Wada, Yusuke, Matsuyama, Satoshi, Mori, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer therapies Cell Line, Tumor Communication Dog Diseases - genetics Dog Diseases - radiotherapy Dogs Down-Regulation Drug dosages Gene Expression Regulation, Neoplastic Kinases Medical research Melanoma Melanoma - genetics Melanoma - radiotherapy Melanoma - veterinary Melanoma, Cutaneous Malignant MicroRNAs MicroRNAs - genetics miRNA PTEN Phosphohydrolase - genetics PTEN protein Radiation Radiation therapy Radiation Tolerance Radioresistance Radiosensitivity Radiosensitizers Skin cancer Skin Neoplasms - genetics Skin Neoplasms - radiotherapy Skin Neoplasms - veterinary Veterinary medicine
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