In-house Implementation of Tumor Mutational Burden Testing to Predict Durable Clinical Benefit in Non-small Cell Lung Cancer and Melanoma Patients

Tumor mutational burden (TMB) has emerged as an important potential biomarker for prediction of response to immune-checkpoint inhibitors (ICIs), notably in non-small cell lung cancer (NSCLC). However, its in-house assessment in routine clinical practice is currently challenging and validation is urg...

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Veröffentlicht in:Cancers 2019-08, Vol.11 (9), p.1271
Hauptverfasser: Heeke, Simon, Benzaquen, Jonathan, Long-Mira, Elodie, Audelan, Benoit, Lespinet, Virginie, Bordone, Olivier, Lalvée, Salomé, Zahaf, Katia, Poudenx, Michel, Humbert, Olivier, Montaudié, Henri, Dugourd, Pierre-Michel, Chassang, Madleen, Passeron, Thierry, Delingette, Hervé, Marquette, Charles-Hugo, Hofman, Véronique, Stenzinger, Albrecht, Ilié, Marius, Hofman, Paul
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Sprache:eng
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