Genomic architecture of Shh-dependent cochlear morphogenesis

The mammalian cochlea develops from a ventral outgrowth of the otic vesicle in response to Shh signaling. Mouse embryos lacking Shh or its essential signal transduction components display cochlear agenesis; however, a detailed understanding of the transcriptional network mediating this process is un...

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Veröffentlicht in:Development (Cambridge) 2019-09, Vol.146 (18)
Hauptverfasser: Muthu, Victor, Rohacek, Alex M, Yao, Yao, Rakowiecki, Staci M, Brown, Alexander S, Zhao, Ying-Tao, Meyers, James, Won, Kyoung-Jae, Ramdas, Shweta, Brown, Christopher D, Peterson, Kevin A, Epstein, Douglas J
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Sprache:eng
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