Selective Immunolesions of Cholinergic Neurons in Mice: Effects on Neuroanatomy, Neurochemistry, and Behavior

The ability to selectively lesion mouse basal forebrain cholinergic neurons would permit experimental examination of interactions between cholinergic functional loss and genetic factors associated with neurodegenerative disease. We developed a selective toxin for mouse basal forebrain cholinergic ne...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of neuroscience 2001-10, Vol.21 (20), p.8164-8173
Hauptverfasser:	Berger-Sweeney, Joanne, Stearns, Nancy A, Murg, Stephanie L, Floerke-Nashner, Laura R, Lappi, Douglas A, Baxter, Mark G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - chemistry Antibody Specificity Behavior, Animal - drug effects Behavior, Animal - physiology Cell Count Cell Survival - drug effects Cells, Cultured Choline O-Acetyltransferase - deficiency Choline O-Acetyltransferase - metabolism Corpus Striatum - cytology Corpus Striatum - drug effects Corpus Striatum - metabolism Dose-Response Relationship, Drug Female Glutamate Decarboxylase - metabolism Hippocampus - cytology Hippocampus - drug effects Hippocampus - metabolism Immunohistochemistry Immunotoxins - administration & dosage Immunotoxins - chemistry Injections, Intraventricular Male Maze Learning - drug effects Mice Mice, Inbred C57BL N-Glycosyl Hydrolases Neocortex - cytology Neocortex - drug effects Neocortex - metabolism Neurons - cytology Neurons - drug effects Neurons - metabolism Plant Proteins - chemistry Prosencephalon - cytology Prosencephalon - drug effects Prosencephalon - metabolism Receptor, Nerve Growth Factor - antagonists & inhibitors Receptor, Nerve Growth Factor - biosynthesis Ribosome Inactivating Proteins, Type 1
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!