Albumin-bioinspired iridium oxide nanoplatform with high photothermal conversion efficiency for synergistic chemo-photothermal of osteosarcoma

Protein-based nanocarriers with inherent biocompatibility have been widely served as building blocks to construct versatile therapeutic nanoplatforms. Herein, bovine serum albumin-iridium oxide nanoparticles (denoted BSA-IrO 2 NPs) are successfully synthesized via one-step biomineralization approach...

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Veröffentlicht in:	Drug delivery 2019-01, Vol.26 (1), p.918-927
Hauptverfasser:	Gu, Wenguang, Zhang, Tao, Gao, Junsheng, Wang, Yi, Li, Dejian, Zhao, Ziwen, Jiang, Bo, Dong, Zhiwei, Liu, Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Animals Biocompatibility biomineralization Bone cancer Bone Neoplasms - drug therapy bovine serum albumin Cancer therapies Cardiology Chemotherapy Cytotoxicity Doxorubicin - chemistry Doxorubicin - pharmacology Drug Delivery Systems - methods Drug Liberation - drug effects Efficiency Female Gadolinium oxide Humans Iridium - chemistry Iridium - pharmacology Iridium oxide Lasers Metal oxides Mice Mice, Inbred BALB C Mice, Nude Nanomaterials Nanoparticles Nanoparticles - chemistry Orthopedics Osteosarcoma - drug therapy Phototherapy - methods photothermal Proteins Sarcoma Serum Albumin, Bovine - chemistry Silicon Dioxide - chemistry synergistic therapy
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