Growth Cone Collapse Induced by Semaphorin 3A Requires 12/15-Lipoxygenase

Detection of a repellent factor, such as a semaphorin (Sema), causes localized collapse of the growth cone and directs the neurite away from the repellent. Growth cone collapse results from concomitant cytoskeletal rearrangements and detachment of adhesion sites from the extracellular matrix, via mo...

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