Integrated Treatment With Stapled Haemorrhoidopexy and Proctonorm® of Haemorrhoidal Disease
This retrospective study was performed in patients undergoing Stapled Haemorrhoidopexy (SH) who were post-operatively treated with Proctonorm® with the aim of assessing its effect on early and late haemorrhoidal-related symptoms. Forty-six males and 54 females received Proctonorm® (one tablet twice...
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| Veröffentlicht in: | In vivo (Athens) 2019-09, Vol.33 (5), p.1671-1675 |
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| creator | Reboa, Giuliano Gipponi, Marco Fregatti, Piero Depaoli, Francesca |
| description | This retrospective study was performed in patients undergoing Stapled Haemorrhoidopexy (SH) who were post-operatively treated with Proctonorm® with the aim of assessing its effect on early and late haemorrhoidal-related symptoms.
Forty-six males and 54 females received Proctonorm® (one tablet twice daily for 14 days) and Ketoprofene R (200 mg, one tablet twice daily, as requested).
"Early Complication Score" (0-12) two days after surgery was 2.02±1.03; pain VAS (Visual Analogue Scale) (0-10) was 1.21±0.89, and the number of anti-inflammatory tablets was 4.24±1.06. At 40-day post-operative assessment, seven patients had post-operative complications with "Late Complication Score" (0-20) of 0.34±0.68. At six-month follow-up, a high index of patient satisfaction (VAS=9.39±0.24) was self-reported with 75% reduction in CSS (Constipation Scoring System) (1.95±2.58) compared to preoperative scores; "Late Complication Score" was 0.
The specific target activity of Proctonorm® at the microcircular level may be effective in patients undergoing SH in order to reduce the inflammatory response of residual haemorrhoids while waiting for stable resolution of symptoms within one or two weeks. |
| doi_str_mv | 10.21873/invivo.11654 |
| format | Article |
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Forty-six males and 54 females received Proctonorm® (one tablet twice daily for 14 days) and Ketoprofene R (200 mg, one tablet twice daily, as requested).
"Early Complication Score" (0-12) two days after surgery was 2.02±1.03; pain VAS (Visual Analogue Scale) (0-10) was 1.21±0.89, and the number of anti-inflammatory tablets was 4.24±1.06. At 40-day post-operative assessment, seven patients had post-operative complications with "Late Complication Score" (0-20) of 0.34±0.68. At six-month follow-up, a high index of patient satisfaction (VAS=9.39±0.24) was self-reported with 75% reduction in CSS (Constipation Scoring System) (1.95±2.58) compared to preoperative scores; "Late Complication Score" was 0.
The specific target activity of Proctonorm® at the microcircular level may be effective in patients undergoing SH in order to reduce the inflammatory response of residual haemorrhoids while waiting for stable resolution of symptoms within one or two weeks.</description><identifier>ISSN: 0258-851X</identifier><identifier>EISSN: 1791-7549</identifier><identifier>DOI: 10.21873/invivo.11654</identifier><identifier>PMID: 31471422</identifier><language>eng</language><publisher>Greece: International Institute of Anticancer Research</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Female ; Hemorrhoidectomy - adverse effects ; Hemorrhoidectomy - methods ; Hemorrhoids - surgery ; Humans ; Male ; Middle Aged ; Postoperative Complications ; Surgical Stapling ; Treatment Outcome ; Young Adult</subject><ispartof>In vivo (Athens), 2019-09, Vol.33 (5), p.1671-1675</ispartof><rights>Copyright© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.</rights><rights>Copyright 2019, International Institute of Anticancer Research 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755022/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755022/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31471422$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Reboa, Giuliano</creatorcontrib><creatorcontrib>Gipponi, Marco</creatorcontrib><creatorcontrib>Fregatti, Piero</creatorcontrib><creatorcontrib>Depaoli, Francesca</creatorcontrib><title>Integrated Treatment With Stapled Haemorrhoidopexy and Proctonorm® of Haemorrhoidal Disease</title><title>In vivo (Athens)</title><addtitle>In Vivo</addtitle><description>This retrospective study was performed in patients undergoing Stapled Haemorrhoidopexy (SH) who were post-operatively treated with Proctonorm® with the aim of assessing its effect on early and late haemorrhoidal-related symptoms.
Forty-six males and 54 females received Proctonorm® (one tablet twice daily for 14 days) and Ketoprofene R (200 mg, one tablet twice daily, as requested).
"Early Complication Score" (0-12) two days after surgery was 2.02±1.03; pain VAS (Visual Analogue Scale) (0-10) was 1.21±0.89, and the number of anti-inflammatory tablets was 4.24±1.06. At 40-day post-operative assessment, seven patients had post-operative complications with "Late Complication Score" (0-20) of 0.34±0.68. At six-month follow-up, a high index of patient satisfaction (VAS=9.39±0.24) was self-reported with 75% reduction in CSS (Constipation Scoring System) (1.95±2.58) compared to preoperative scores; "Late Complication Score" was 0.
The specific target activity of Proctonorm® at the microcircular level may be effective in patients undergoing SH in order to reduce the inflammatory response of residual haemorrhoids while waiting for stable resolution of symptoms within one or two weeks.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Female</subject><subject>Hemorrhoidectomy - adverse effects</subject><subject>Hemorrhoidectomy - methods</subject><subject>Hemorrhoids - surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Postoperative Complications</subject><subject>Surgical Stapling</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>0258-851X</issn><issn>1791-7549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkU1LAzEQhoMotn4cvcoevazmazfZiyB-VRAUVPQghGwybSO7m5qkxf4pf4S_zNKq1NPAzMM7MzwIHRB8TIkU7MR1Mzfzx4SUBd9AfSIqkouCV5uoj2khc1mQlx7aifEN41JgTLdRjxEuCKe0j15vugSjoBPY7DGATi10KXt2aZw9JD1pFu2BhtaHMPbO-gl8zDPd2ew-eJN850P79Zn54Tqkm-zCRdAR9tDWUDcR9n_qLnq6unw8H-S3d9c352e3uWGcpbxiRFZQaoONNULW0vKSYcEt1JSBKSmu6VBKWwppuKgZ0LoucMGx0MxyydkuOl3lTqZ1C9YsXgi6UZPgWh3mymun_k86N1YjP1OlKApM6SLg6Ccg-PcpxKRaFw00je7AT6OiVDKCK7zcla9QE3yMAYZ_awhWSyNqZUQtjSz4w_Xb_uhfBewbqt6Lfw</recordid><startdate>20190901</startdate><enddate>20190901</enddate><creator>Reboa, Giuliano</creator><creator>Gipponi, Marco</creator><creator>Fregatti, Piero</creator><creator>Depaoli, Francesca</creator><general>International Institute of Anticancer Research</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20190901</creationdate><title>Integrated Treatment With Stapled Haemorrhoidopexy and Proctonorm® of Haemorrhoidal Disease</title><author>Reboa, Giuliano ; Gipponi, Marco ; Fregatti, Piero ; Depaoli, Francesca</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c343t-93189e6ac0cdc78b8d463074deb23ec620b2f88d678c47b3e2bb505407a3d4843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Female</topic><topic>Hemorrhoidectomy - adverse effects</topic><topic>Hemorrhoidectomy - methods</topic><topic>Hemorrhoids - surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Postoperative Complications</topic><topic>Surgical Stapling</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Reboa, Giuliano</creatorcontrib><creatorcontrib>Gipponi, Marco</creatorcontrib><creatorcontrib>Fregatti, Piero</creatorcontrib><creatorcontrib>Depaoli, Francesca</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>In vivo (Athens)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Reboa, Giuliano</au><au>Gipponi, Marco</au><au>Fregatti, Piero</au><au>Depaoli, Francesca</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Integrated Treatment With Stapled Haemorrhoidopexy and Proctonorm® of Haemorrhoidal Disease</atitle><jtitle>In vivo (Athens)</jtitle><addtitle>In Vivo</addtitle><date>2019-09-01</date><risdate>2019</risdate><volume>33</volume><issue>5</issue><spage>1671</spage><epage>1675</epage><pages>1671-1675</pages><issn>0258-851X</issn><eissn>1791-7549</eissn><abstract>This retrospective study was performed in patients undergoing Stapled Haemorrhoidopexy (SH) who were post-operatively treated with Proctonorm® with the aim of assessing its effect on early and late haemorrhoidal-related symptoms.
Forty-six males and 54 females received Proctonorm® (one tablet twice daily for 14 days) and Ketoprofene R (200 mg, one tablet twice daily, as requested).
"Early Complication Score" (0-12) two days after surgery was 2.02±1.03; pain VAS (Visual Analogue Scale) (0-10) was 1.21±0.89, and the number of anti-inflammatory tablets was 4.24±1.06. At 40-day post-operative assessment, seven patients had post-operative complications with "Late Complication Score" (0-20) of 0.34±0.68. At six-month follow-up, a high index of patient satisfaction (VAS=9.39±0.24) was self-reported with 75% reduction in CSS (Constipation Scoring System) (1.95±2.58) compared to preoperative scores; "Late Complication Score" was 0.
The specific target activity of Proctonorm® at the microcircular level may be effective in patients undergoing SH in order to reduce the inflammatory response of residual haemorrhoids while waiting for stable resolution of symptoms within one or two weeks.</abstract><cop>Greece</cop><pub>International Institute of Anticancer Research</pub><pmid>31471422</pmid><doi>10.21873/invivo.11654</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | In vivo (Athens), 2019-09, Vol.33 (5), p.1671-1675 |
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| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Adult Aged Aged, 80 and over Female Hemorrhoidectomy - adverse effects Hemorrhoidectomy - methods Hemorrhoids - surgery Humans Male Middle Aged Postoperative Complications Surgical Stapling Treatment Outcome Young Adult |
| title | Integrated Treatment With Stapled Haemorrhoidopexy and Proctonorm® of Haemorrhoidal Disease |
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