Unified Staging System for Lewy Body Disorders: Clinicopathologic Correlations and Comparison to Braak Staging

Abstract This study was designed to correlate clinical findings with the extent of pathologic a-synuclein (aSyn) in the brain using the Unified Staging System for Lewy Body disorders (USSLB). Data from 280 cases from the Arizona Study of Aging and Neurodegenerative Disorders are presented. Each case...

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Veröffentlicht in:	Journal of neuropathology and experimental neurology 2019-10, Vol.78 (10), p.891-899
Hauptverfasser:	Adler, Charles H, Beach, Thomas G, Zhang, Nan, Shill, Holly A, Driver-Dunckley, Erika, Caviness, John N, Mehta, Shyamal H, Sabbagh, Marwan N, Serrano, Geidy E, Sue, Lucia I, Belden, Christine M, Powell, Jessica, Jacobson, Sandra A, Zamrini, Edward, Shprecher, David, Davis, Kathryn J, Dugger, Brittany N, Hentz, Joseph G
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over alpha-Synuclein - metabolism Brain - metabolism Brain - pathology Brain diseases Cognitive ability Cognitive Dysfunction - diagnosis Cognitive Dysfunction - metabolism Cognitive Dysfunction - pathology Diagnosis Female Humans Lewy Bodies - metabolism Lewy Bodies - pathology Lewy body disease Lewy Body Disease - diagnosis Lewy Body Disease - metabolism Lewy Body Disease - pathology Male Methods Neurologic examination Olfaction disorders Original Parkinson's disease Severity of Illness Index
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