Preeclampsia: Maternal Systemic Vascular Disorder Caused by Generalized Endothelial Dysfunction Due to Placental Antiangiogenic Factors

Preeclampsia, a systemic vascular disorder characterized by new-onset hypertension and proteinuria after 20 weeks of gestation, is the leading cause of maternal and perinatal morbidity and mortality. Maternal endothelial dysfunction caused by placental factors has long been accepted with respect to...

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Veröffentlicht in:	International journal of molecular sciences 2019-08, Vol.20 (17), p.4246
Hauptverfasser:	Tomimatsu, Takuji, Mimura, Kazuya, Matsuzaki, Shinya, Endo, Masayuki, Kumasawa, Keiichi, Kimura, Tadashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - metabolism Antiangiogenics Antiphospholipid syndrome Blood pressure Cancer Chronic conditions Creatinine Diabetes Diabetes mellitus Disease Endothelium Endothelium, Vascular - physiopathology Enzymes Female Genomes Gestation Growth factors Humans Hypertension Immunology Kidney diseases Kinases Nitric oxide Pathogenesis Placenta Placenta - physiopathology Pre-eclampsia Pre-Eclampsia - diagnosis Pre-Eclampsia - physiopathology Pre-Eclampsia - prevention & control Pre-Eclampsia - therapy Preeclampsia Pregnancy Protein-tyrosine kinase Proteinuria Review Risk analysis Risk Factors Systemic lupus erythematosus Tyrosine Urine Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism Womens health
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