Novel tyrosinase inhibitory peptide with free radical scavenging ability

Tyrosinase is a key enzyme involved in melanin synthesis. Therefore, various tyrosinase inhibitors have been screened by researchers in recent years. In the present study, we discovered a novel tyrosinase inhibitor, a peptide ECGYF (named EF-5), with free radical scavenging ability. The effect of ty...

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Veröffentlicht in:	Journal of enzyme inhibition and medicinal chemistry 2019-01, Vol.34 (1), p.1633-1640
Hauptverfasser:	Shen, Zhiwei, Wang, Yujiao, Guo, Zhen, Tan, Tingyuan, Zhang, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Dose-Response Relationship, Drug Enzyme Inhibitors - chemical synthesis Enzyme Inhibitors - chemistry Enzyme Inhibitors - pharmacology Free Radical Scavengers - chemical synthesis Free Radical Scavengers - chemistry Free Radical Scavengers - pharmacology Humans Melanin Molecular Docking Simulation Molecular Structure Monophenol Monooxygenase - antagonists & inhibitors Monophenol Monooxygenase - metabolism Peptides - chemical synthesis Peptides - chemistry Peptides - pharmacology radical scavenging Research Paper Structure-Activity Relationship Tumor Cells, Cultured tyrosinase inhibitory peptide
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