Corticotropin Releasing Hormone Type 2 Receptors in the Dorsal Raphe Nucleus Mediate the Behavioral Consequences of Uncontrollable Stress

Uncontrollable shock produces a constellation of behavioral changes that are not observed after equivalent escapable shock. These include interference with escape and potentiation of fear conditioning. The activation of corticotropin-releasing hormone (CRH) receptors within the caudal dorsal raphe n...

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Veröffentlicht in:	The Journal of neuroscience 2003-02, Vol.23 (3), p.1019-1025
Hauptverfasser:	Hammack, Sayamwong E, Schmid, Megan J, LoPresti, Matthew L, Der-Avakian, Andre, Pellymounter, Mary Ann, Foster, Alan C, Watkins, Linda R, Maier, Steven F
Format:	Artikel
Sprache:	eng
Schlagworte:	Amygdala - drug effects Amygdala - physiology Aniline Compounds - pharmacology Animals Behavior, Animal - drug effects Behavior, Animal - physiology Corticotropin-Releasing Hormone - pharmacology Dose-Response Relationship, Drug Electroshock Escape Reaction - drug effects Escape Reaction - physiology Fear - physiology Helplessness, Learned Male Microinjections Motor Activity - drug effects Motor Activity - physiology Peptide Fragments - pharmacology Pyrimidines - pharmacology Raphe Nuclei - drug effects Raphe Nuclei - metabolism Rats Rats, Sprague-Dawley Receptors, Corticotropin-Releasing Hormone - agonists Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors Receptors, Corticotropin-Releasing Hormone - metabolism Serotonin - metabolism Stress, Physiological - physiopathology Urocortins
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