Synaptic Transport of Human Immunodeficiency Virus-Tat Protein Causes Neurotoxicity and Gliosis in Rat Brain

Neurodegeneration, synaptic alterations, and gliosis are prominent features of human immunodeficiency virus (HIV) encephalitis, but HIV encephalitis is distinct from other viral encephalitides because neurodegeneration occurs in uninfected neurons at anatomical sites that are often distant from the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of neuroscience 2003-09, Vol.23 (23), p.8417-8422
Hauptverfasser:	Bruce-Keller, Annadora J, Chauhan, Ashok, Dimayuga, Filomena O, Gee, Jillian, Keller, Jeffrey N, Nath, Avindra
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS Dementia Complex - etiology Animals Axonal Transport - physiology Behavior, Animal - drug effects Brain - drug effects Brain - metabolism Brain - pathology Brief Communications Cell Survival - drug effects Corpus Striatum - drug effects Corpus Striatum - metabolism Corpus Striatum - pathology Gene Products, tat - genetics Gene Products, tat - metabolism Gene Products, tat - toxicity Gene Transfer Techniques Glioma - metabolism gliosis Gliosis - chemically induced Gliosis - pathology Hippocampus - drug effects Hippocampus - metabolism Hippocampus - pathology Human immunodeficiency virus Male Motor Activity - drug effects Neoplasm Transplantation Neuroglia - pathology Neurons - drug effects Neurons - pathology Rats Rats, Sprague-Dawley Stereotaxic Techniques Substantia Nigra - pathology Synapses - metabolism tat Gene Products, Human Immunodeficiency Virus
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!