Inhibition of vascular smooth muscle cell calcification by ATP analogues

Arterial medial calcification (AMC) has been associated with phenotypic changes in vascular smooth muscle cells (VSMCs) that reportedly makes them more osteoblast-like. Previous work has shown that ATP/UTP can inhibit AMC directly via P2 receptors and indirectly by NPP1-mediated hydrolysis to produc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Purinergic signalling 2019-09, Vol.15 (3), p.315-326
Hauptverfasser:	Patel, Jessal J., Bourne, Lucie E., Millán, José Luis, Arnett, Timothy R., MacRae, Vicky E., Wheeler-Jones, Caroline P. D., Orriss, Isabel R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - analogs & derivatives Adenosine Triphosphate - pharmacology Animals Apoptosis Biomedical and Life Sciences Biomedicine Calcification Calcification (ectopic) Calcinosis - metabolism Calcinosis - pathology Cancer Research Cbfa-1 protein Cell culture Human Physiology Mice Mice, Knockout Mineralization Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - metabolism Muscle, Smooth, Vascular - pathology Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - metabolism Myocytes, Smooth Muscle - pathology Neurosciences Nucleotides Original Original Article Osteopontin Pharmacology/Toxicology Phosphoric Diester Hydrolases - metabolism Purine P2 receptors Purine P2X receptors Pyrophosphatases - metabolism Receptors, Purinergic P2 - metabolism Smooth muscle
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!