Membrane capacitance recordings resolve dynamics and complexity of receptor-mediated endocytosis in Wnt signalling

Receptor-mediated endocytosis is an essential process in signalling pathways for activation of intracellular signalling cascades. One example is the Wnt signalling pathway that seems to depend on endocytosis of the ligand-receptor complex for initiation of Wnt signal transduction. To date, the roles...

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Veröffentlicht in:	Scientific reports 2019-09, Vol.9 (1), p.12999-11, Article 12999
Hauptverfasser:	Bandmann, Vera, Mirsanaye, Ann Schirin, Schäfer, Johanna, Thiel, Gerhard, Holstein, Thomas, Mikosch-Wersching, Melanie
Format:	Artikel
Sprache:	eng
Schlagworte:	14/19 631/57/1461 631/80/86/2370 9/74 96/34 Cell Membrane - metabolism Clathrin Clathrin - metabolism Endocytosis HEK293 Cells Humanities and Social Sciences Humans Intracellular signalling Ligands Membrane capacitance Membranes multidisciplinary Science Science (multidisciplinary) Signal transduction Wnt protein Wnt Signaling Pathway Wnt-5a Protein - genetics Wnt-5a Protein - metabolism Wnt3A Protein - genetics Wnt3A Protein - metabolism
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