Apixaban enhances endogenous fibrinolysis in patients with atrial fibrillation

Abstract Aims Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which strongly relates to improved functional outcome. The impact of oral anticoagulants on endogenous fibrinolysis is unknown. Our aim was to test the h...

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Veröffentlicht in:	Europace (London, England) England), 2019-09, Vol.21 (9), p.1297-1306
Hauptverfasser:	Spinthakis, Nikolaos, Gue, Ying, Farag, Mohamed, Srinivasan, Manivannan, Wellsted, David, Arachchillage, Deepa R J, Lip, Gregory Y H, Gorog, Diana A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anticoagulants - therapeutic use Aspirin - therapeutic use Atrial Fibrillation - complications Atrial Fibrillation - drug therapy Blood Coagulation Tests Clinical Research Cross-Sectional Studies Factor Xa Inhibitors - therapeutic use Female Fibrin Clot Lysis Time Fibrinolysis - physiology Humans Ischemic Stroke - etiology Ischemic Stroke - prevention & control Longitudinal Studies Male Middle Aged Platelet Aggregation Inhibitors - therapeutic use Prospective Studies Pyrazoles - therapeutic use Pyridones - therapeutic use Thrombelastography Warfarin - therapeutic use
Online-Zugang:	Volltext
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